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The rs1634330 Polymorphisms in the SOST Gene Are Associated with Body Composition in Chinese Nuclear Families with Male Offspring

التفاصيل البيبلوغرافية
العنوان: The rs1634330 Polymorphisms in the SOST Gene Are Associated with Body Composition in Chinese Nuclear Families with Male Offspring
المؤلفون: Luyue Qi, Lianyong Liu, Li Li, Weiwei Hu, Wenzhen Fu, Ji Hu, Youjia Xu, Zhenlin Zhang
المصدر: International Journal of Endocrinology, Vol 2021 (2021)
بيانات النشر: Hindawi Limited, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the endocrine glands. Clinical endocrinology
مصطلحات موضوعية: Diseases of the endocrine glands. Clinical endocrinology, RC648-665
الوصف: Objective. The purpose of this study was to explore the effect of the SOST gene polymorphisms on body composition in Chinese nuclear families with male offspring. Methods. 1,016 individuals were recruited from 335 Chinese nuclear families with male offspring. The nuclear families consist of at least one male offspring aged 18 to 44. We genotyped the 10 tagged single-nucleotide polymorphisms (SNPs) in SOST gene (rs7220711, rs865429, rs851057, rs1708635, rs2023794, rs1234612, rs74252774, rs1634330, rs851058, and rs1513670) in all the above people. We used dual-energy X-ray absorptiometry to measure the composition of the human body. The quantitative transmission disequilibrium test (QTDT) was used to analyze the associations of the SNPs with the body composition. Results. QTDT analysis showed that rs1634330 was significantly associated with trunk LM P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1687-8337
1687-8345
العلاقة: https://doaj.org/toc/1687-8337Test; https://doaj.org/toc/1687-8345Test
DOI: 10.1155/2021/6698822
الوصول الحر: https://doaj.org/article/d4298dab5f424c92b91e9cf849bda81cTest
رقم الانضمام: edsdoj.4298dab5f424c92b91e9cf849bda81c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16878337
16878345
DOI:10.1155/2021/6698822