دورية أكاديمية

Long-term safety of tenapanor in people with irritable bowel syndrome with constipation from the T3MPO-3 study: plain language summary of publication

التفاصيل البيبلوغرافية
العنوان: Long-term safety of tenapanor in people with irritable bowel syndrome with constipation from the T3MPO-3 study: plain language summary of publication
المؤلفون: Anthony J. Lembo, Susan Edelstein, David P. Rosenbaum, Ceciel Rooker, Jeffrey D. Roberts, William D. Chey
المصدر: Therapeutic Advances in Gastroenterology, Vol 17 (2024)
بيانات النشر: SAGE Publishing, 2024.
سنة النشر: 2024
المجموعة: LCC:Diseases of the digestive system. Gastroenterology
مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869
الوصف: This document provides a short summary of the T3MPO-3 study, which was published in Neurogastroenterology and Motility in September 2023. At the end of this summary, there are links to websites where you can find more information about this study. Tenapanor (IBSRELA®) is a newly available medicine in the United States. It is used to treat irritable bowel syndrome with constipation (IBS-C) in people aged 18 years and older. In 2 large clinical trials, tenapanor was shown to improve the symptoms of IBS-C. People with IBS-C often need to take long-term medicines to keep their symptoms under control. As a result, this study, called T3MPO-3 , was undertaken to investigate whether there are any possible side effects associated with the long-term use of tenapanor in adults with IBS-C. There were 312 people who had taken part in either of the original 2 trials and took part in this study, with 90 receiving tenapanor for at least 1 year. Loose or watery stool (diarrhea) was the most common side effect, and most cases were mild or moderate. No people died in any of these studies.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1756-2848
17562848
العلاقة: https://doaj.org/toc/1756-2848Test
DOI: 10.1177/17562848241237196
الوصول الحر: https://doaj.org/article/a42748ddee794bc48998e93ed4093048Test
رقم الانضمام: edsdoj.42748ddee794bc48998e93ed4093048
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17562848
DOI:10.1177/17562848241237196