دورية أكاديمية
Successful Treatment of Disseminated Granuloma Annulare with Upadacitinib
| العنوان: | Successful Treatment of Disseminated Granuloma Annulare with Upadacitinib |
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| المؤلفون: | Axel De Greef, Ghita Benjelloun, Evelyne Harkemanne, Marie Baeck |
| المصدر: | Dermatology and Therapy, Vol 14, Iss 3, Pp 813-817 (2024) |
| بيانات النشر: | Adis, Springer Healthcare, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | Granuloma annulare, JAK inhibitor, Upadacitinib, Effectiveness, Tolerance, Dermatology, RL1-803 |
| الوصف: | Abstract Disseminated granuloma annulare (DGA) is an inflammatory skin disorder characterized by more than 10 erythematous, raised, ring-shaped plaques. Its treatment remains challenging, with conventional therapies showing variable efficacy. We report the case of a woman in her 50s with a 2-year history of DGA refractory to multiple treatments. Given the recent evidence of the role of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in the granuloma annulare pathophysiology, treatment with upadacitinib 30 mg per day was started with rapid effectiveness and good tolerance. This case underscores the potential of JAK inhibitors as promising therapeutic options for recalcitrant granuloma annulare. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2193-8210 2190-9172 |
| العلاقة: | https://doaj.org/toc/2193-8210Test; https://doaj.org/toc/2190-9172Test |
| DOI: | 10.1007/s13555-024-01117-z |
| الوصول الحر: | https://doaj.org/article/40fce661a7654b80ab4190cd6e79981bTest |
| رقم الانضمام: | edsdoj.40fce661a7654b80ab4190cd6e79981b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21938210 21909172 |
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| DOI: | 10.1007/s13555-024-01117-z |