دورية أكاديمية
Evolution of Avian Influenza Virus (H3) with Spillover into Humans, China
| العنوان: | Evolution of Avian Influenza Virus (H3) with Spillover into Humans, China |
|---|---|
| المؤلفون: | Jiaying Yang, Ye Zhang, Lei Yang, Xiyan Li, Hong Bo, Jia Liu, Min Tan, Wenfei Zhu, Yuelong Shu, Dayan Wang |
| المصدر: | Emerging Infectious Diseases, Vol 29, Iss 6, Pp 1191-1201 (2023) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Avian influenza virus, H3, reassortment, viruses, genotype, surveillance, Medicine, Infectious and parasitic diseases, RC109-216 |
| الوصف: | The continuous evolution of avian influenza viruses (AIVs) of subtype H3 in China and the emergence of human infection with AIV subtype H3N8 highlight their threat to public health. Through surveillance in poultry-associated environments during 2009–2022, we isolated and sequenced 188 H3 AIVs across China. Performing large-scale sequence analysis with publicly available data, we identified 4 sublineages of H3 AIVs established in domestic ducks in China via multiple introductions from wild birds from Eurasia. Using full-genome analysis, we identified 126 distinct genotypes, of which the H3N2 G23 genotype predominated recently. H3N8 G25 viruses, which spilled over from birds to humans, might have been generated by reassortment between H3N2 G23, wild bird H3N8, and poultry H9N2 before February 2021. Mammal-adapted and drug-resistance substitutions occasionally occurred in H3 AIVs. Ongoing surveillance for H3 AIVs and risk assessment are imperative for potential pandemic preparedness. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1080-6040 1080-6059 |
| العلاقة: | https://wwwnc.cdc.gov/eid/article/29/6/22-1786_articleTest; https://doaj.org/toc/1080-6040Test; https://doaj.org/toc/1080-6059Test |
| DOI: | 10.3201/eid2906.221786 |
| الوصول الحر: | https://doaj.org/article/40732b2f64694f2dba8f5cf84fe416d4Test |
| رقم الانضمام: | edsdoj.40732b2f64694f2dba8f5cf84fe416d4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10806040 10806059 |
|---|---|
| DOI: | 10.3201/eid2906.221786 |