دورية أكاديمية
Development and clinical validation of Swaasa AI platform for screening and prioritization of pulmonary TB
| العنوان: | Development and clinical validation of Swaasa AI platform for screening and prioritization of pulmonary TB |
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| المؤلفون: | Gayatri Devi Yellapu, Gowrisree Rudraraju, Narayana Rao Sripada, Baswaraj Mamidgi, Charan Jalukuru, Priyanka Firmal, Venkat Yechuri, Sowmya Varanasi, Venkata Sudhakar Peddireddi, Devi Madhavi Bhimarasetty, Sidharth Kanisetti, Niranjan Joshi, Prasant Mohapatra, Kiran Pamarthi |
| المصدر: | Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023) |
| بيانات النشر: | Nature Portfolio, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract Acoustic signal analysis has been employed in various medical devices. However, studies involving cough sound analysis to screen the potential pulmonary tuberculosis (PTB) suspects are very few. The main objective of this cross-sectional validation study was to develop and validate the Swaasa AI platform to screen and prioritize at risk patients for PTB based on the signature cough sound as well as symptomatic information provided by the subjects. The voluntary cough sound data was collected at Andhra Medical College-India. An Algorithm based on multimodal convolutional neural network architecture and feedforward artificial neural network (tabular features) was built and validated on a total of 567 subjects, comprising 278 positive and 289 negative PTB cases. The output from these two models was combined to detect the likely presence (positive cases) of PTB. In the clinical validation phase, the AI-model was found to be 86.82% accurate in detecting the likely presence of PTB with 90.36% sensitivity and 84.67% specificity. The pilot testing of model was conducted at a peripheral health care centre, RHC Simhachalam-India on 65 presumptive PTB cases. Out of which, 15 subjects truly turned out to be PTB positive with a positive predictive value of 75%. The validation results obtained from the model are quite encouraging. This platform has the potential to fulfil the unmet need of a cost-effective PTB screening method. It works remotely, presents instantaneous results, and does not require a highly trained operator. Therefore, it could be implemented in various inaccessible, resource-poor parts of the world. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| العلاقة: | https://doaj.org/toc/2045-2322Test |
| DOI: | 10.1038/s41598-023-31772-9 |
| الوصول الحر: | https://doaj.org/article/3f56bae46865478dab979528673f4138Test |
| رقم الانضمام: | edsdoj.3f56bae46865478dab979528673f4138 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-023-31772-9 |