دورية أكاديمية
Concepts and targets in triple-negative breast cancer: recent results and clinical implications
| العنوان: | Concepts and targets in triple-negative breast cancer: recent results and clinical implications |
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| المؤلفون: | Poornima Saha, Rita Nanda |
| المصدر: | Therapeutic Advances in Medical Oncology, Vol 8 (2016) |
| بيانات النشر: | SAGE Publishing, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Triple-negative breast cancer (TNBC) is a heterogeneous disease in which tumors are defined by lack of expression of the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2) receptor. No targeted therapies are available for the treatment of TNBC, and chemotherapy remains the standard of care. Gene expression profiling has identified six distinct molecular subtypes of TNBC. The identification of novel targets, coupled with the development of therapies for different subsets of TNBC, holds great promise for the future treatment of this aggressive form of breast cancer. This review focuses on novel therapies in development for the treatment of TNBC. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1758-8340 1758-8359 17588340 |
| العلاقة: | https://doaj.org/toc/1758-8340Test; https://doaj.org/toc/1758-8359Test |
| DOI: | 10.1177/1758834016657071 |
| الوصول الحر: | https://doaj.org/article/c38c1acdbc4f4c8a8a18a60ed40d8efcTest |
| رقم الانضمام: | edsdoj.38c1acdbc4f4c8a8a18a60ed40d8efc |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17588340 17588359 |
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| DOI: | 10.1177/1758834016657071 |