دورية أكاديمية
Nutrition in sickle cell disease: recent insights
| العنوان: | Nutrition in sickle cell disease: recent insights |
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| المؤلفون: | Umeakunne K, Hibbert JM |
| المصدر: | Nutrition and Dietary Supplements, Vol Volume 11, Pp 9-17 (2019) |
| بيانات النشر: | Dove Medical Press, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: | Macronutrients, micronutrients, inflammation, Vaso-occlusive crisis (VOC), Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: | Kayellen Umeakunne,1 Jacqueline M Hibbert21Clinical Research Center, Bio-nutrition Core, Morehouse School of Medicine, Atlanta, GA, USA; 2Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA, USAAbstract: A cure for sickle cell anemia (SCA) is not available to all who have inherited this devastating genetically inherited disease. However, increasing knowledge that nutritional problems are fundamental to the severity of the disease, has produced interest in promoting dietary supplementation for treating these patients. This review seeks to emphasize the understanding that both children and adults with sickle cell disease require much higher energy and protein consumption (more macronutrient intake) than healthy individuals and tend to suffer from undernutrition if energy intake is consistently low. Shortages may also exist for micronutrients, eg, Glutathione, which has both anti-inflammatory and anti-oxidant properties. Both chronic inflammation and oxidant stress are central issues for increased sickle cell disease severity. In conclusion, dedicating more effort and resources to establishing recommended dietary reference intakes (DRIs)/recommended dietary allowances (RDAs) for SCA patients is essential, and nutritional intervention should be included as an adjunct treatment in tandem with standard practice.Keywords: macronutrients, micronutrients, inflammation, vaso-occlusive crisis (VOC) |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1179-1489 |
| العلاقة: | https://www.dovepress.com/nutrition-in-sickle-cell-disease-recent-insights-peer-reviewed-article-NDSTest; https://doaj.org/toc/1179-1489Test |
| الوصول الحر: | https://doaj.org/article/2d8040dc429542b2b0c49ff75b7e60f8Test |
| رقم الانضمام: | edsdoj.2d8040dc429542b2b0c49ff75b7e60f8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 11791489 |
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