دورية أكاديمية
Ambulatory blood pressure response to S‐amlodipine in Korean adult patients with uncontrolled essential hypertension: A prospective, observational study
العنوان: | Ambulatory blood pressure response to S‐amlodipine in Korean adult patients with uncontrolled essential hypertension: A prospective, observational study |
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المؤلفون: | Dong Kyun Kim, Joon Ho Ahn, Ki Hong Lee, Si‐Hyuck Kang, Sung Soo Kim, Jin Oh Na, Sang Don Park, Kye Taek Ahn, Jung‐Hee Lee, In Hyun Jung, Jongkwon Seo, Woong Gil Choi |
المصدر: | The Journal of Clinical Hypertension, Vol 24, Iss 3, Pp 350-357 (2022) |
بيانات النشر: | Wiley, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | ambulatory, blood pressure monitoring, chirality, essential hypertension, S‐amlodipine, safety, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Abstract Although amlodipine is recommended as the first‐line therapy for the treatment of hypertension, its use is limited by its potential side effects. S‐amlodipine is expected to be able to minimize side effects of amlodipine with a similar antihypertensive effect by removing the malicious R‐chiral form. However, sustainable blood pressure control with S‐amlodipine has not been well established yet. The purpose of the current study was to evaluate ambulatory blood pressure (ABP) profiles before and after a 12‐week treatment of S‐amlodipine. Patients received once‐daily S‐amlodipine 2.5 or 5 mg. ABP during 24 hr and office blood pressure were measured at baseline and after the 12‐week treatment. Primary endpoints were changes of systolic and diastolic 24 hr ABP. After 12‐week S‐amlodipine treatment, mean systolic ABP (‐15.1 ± 16.2 mmHg, p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1751-7176 1524-6175 |
العلاقة: | https://doaj.org/toc/1524-6175Test; https://doaj.org/toc/1751-7176Test |
DOI: | 10.1111/jch.14442 |
الوصول الحر: | https://doaj.org/article/2a6a44a2587d499ead7db803a615d39dTest |
رقم الانضمام: | edsdoj.2a6a44a2587d499ead7db803a615d39d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17517176 15246175 |
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DOI: | 10.1111/jch.14442 |