التفاصيل البيبلوغرافية
العنوان:
Genome sequencing unveils a regulatory landscape of platelet reactivity
المؤلفون:
Ali R. Keramati , Ming-Huei Chen , Benjamin A. T. Rodriguez , Lisa R. Yanek , Arunoday Bhan , Brady J. Gaynor , Kathleen Ryan , Jennifer A. Brody , Xue Zhong , Qiang Wei , NHLBI Trans-Omics for Precision (TOPMed) Consortium , Kai Kammers , Kanika Kanchan , Kruthika Iyer , Madeline H. Kowalski , Achilleas N. Pitsillides , L. Adrienne Cupples , Bingshan Li , Thorsten M. Schlaeger , Alan R. Shuldiner , Jeffrey R. O’Connell , Ingo Ruczinski , Braxton D. Mitchell , Nauder Faraday , Margaret A. Taub , Lewis C. Becker , Joshua P. Lewis , Rasika A. Mathias , Andrew D. Johnson
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Platelet aggregation is associated with myocardial infarction and stroke. Here, the authors have conducted a whole genome sequencing association study on platelet aggregation, discovering a locus in RGS18, where enhancer assays suggest an effect on activity of haematopoeitic lineage transcription factors.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-021-23470-9
الوصول الحر:
https://doaj.org/article/21f176ab19b541d294b9acdf21deb0aeTest
رقم الانضمام:
edsdoj.21f176ab19b541d294b9acdf21deb0ae
قاعدة البيانات:
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