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Clinical complications after a traumatic brain injury and its relation with brain biomarkers

التفاصيل البيبلوغرافية
العنوان: Clinical complications after a traumatic brain injury and its relation with brain biomarkers
المؤلفون: Oriol Yuguero, Maria Bernal, Joan Farré, Montserrat Martinez-Alonso, Ana Vena, Francisco Purroy
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract We aimed to find out which are the most frequent complications for patients who suffer a traumatic brain injury (TBI) and its relation with brain biomarker levels. We conducted a hospital cohort study with patients who attended the Hospital Emergency Department between 1 June 2018 and 31 December 2020. Different variables were collected such as biomarkers levels after 6 h and 12 h of TBI (S100, NSE, UCHL1 and GFAP), clinical and sociodemographic variables, complementary tests, and complications 48 h and 7 days after TBI. Qualitative variables were analysed with Pearson’s chi-square test, and quantitative variables with the Mann–Whitney U test. A multivariate logistic regression model for the existence of complications one week after discharge was performed to assess the discriminatory capacity of the clinical variables. A total of 51 controls and 540 patients were included in this study. In the TBI group, the mean age was 83 years, and 53.9% of the patients were male. Complications at seven days were associated with the severity of TBI (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
العلاقة: https://doaj.org/toc/2045-2322Test
DOI: 10.1038/s41598-023-47267-6
الوصول الحر: https://doaj.org/article/1ee2b8fdfa8f42b49e5e44c1637b492bTest
رقم الانضمام: edsdoj.1ee2b8fdfa8f42b49e5e44c1637b492b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-47267-6