Background: This study explores the use of tetra-hybrid nanoparticles consisting of gold, silver, alumina, and titania nanocomposites dispersed in a non-Newtonian Casson fluid modelled as blood. The motivation lies in harnessing the synergistic optical, electrical, thermal, and physicochemical properties of the multimodal nanoscale assembly to advance electrokinetic pumping processes. Objectives: The study aims to computationally investigate the complex transport assisted by tailored gold, silver, alumina, and titania dioxide nanoparticles in the tetra-hybrid nanofluid, with potential applications in targeted drug delivery, hyperthermia cancer treatment, Lab-on-Chip devices, and miniaturized biosensors. Methodology: The constructed streaming flow model examines the cumulative influence of viscous heating, Joule heating, conductive thermal, and external laser irradiation. Current simulations examine Casson flows with the integrated nanoparticles by modelling two- and three-dimensional conduits subject to transverse magnetohydrodynamics and localized laser irradiation. Key findings: The solutions provide mathematical predictions and physical insights into the fully coupled velocity, temperature, concentration, and pressure gradient contours. Additional plots examining dimensionless analytes against pertinent profiles, combined with streamlined visualization, further elucidate the multifaceted transport and complex trapping patterns stemming from non-Newtonian rheology. Applications/implications: This multiscale examination reveals performance improvements realizable by leveraging biocompatible tetra-hybrid nanocomposites in electrokinetic flows vital for next-generation biomedical technologies.
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