دورية أكاديمية
Xanthine oxidase inhibitory activity of compounds from Chythrantus claneianus
| العنوان: | Xanthine oxidase inhibitory activity of compounds from Chythrantus claneianus |
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| المؤلفون: | Anar Sahib Gojayev, Jean Jules Kezetas Bankeu, Angelbert Fusi Awantu, Eric René Sieliatchom Nkanwen, Muhammad Shaiq Ali, Bruno Ndjakou Lenta, Akif Alakbar Guliyev, Didérot Tchamo Noungoué, Silvère Augustin Ngouela, Etienne Tsamo |
| المصدر: | Bangladesh Journal of Pharmacology, Vol 8, Iss 1 (2013) |
| بيانات النشر: | Bangladesh Pharmacological Society, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | Chythrantus claneianus, rheumatism, xanthine oxidase inhibitor, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | Phytochemical investigation of the stem bark and the trunk of Chythrantus claneianus led to the isolation of six known compounds named β-sitosterol (1), umbelliferone (2), scopoletin (3), benjaminamide (4), β-sitosterol-3-O-β-D-glucopyranoside (5) and panconoside B (6). All these compounds were isolated for the first time from this plant species. The chemical structures of isolates were elucidated on the basis of 1 and 2 D-NMR spectra and other spectroscopic techniques including UV–vis, FT-IR, HR-ESIMS and HR-FABMS. The isolates were tested in vitro for their inhibitory properties towards xanthine oxidase enzyme. Compounds 2, 3 and 6 showed weak inhibitory activities on the enzyme with IC50 values ranging from 307 µM for compound 6 to 475 µM for compound 3, while the extract and compounds 1, 4 and 5 showed extremely weak activities with inhibition percentage less than 50%. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1991-0088 64364844 |
| العلاقة: | https://www.banglajol.info/index.php/BJP/article/view/13485Test; https://doaj.org/toc/1991-0088Test |
| DOI: | 10.3329/bjp.v8i1.13485 |
| الوصول الحر: | https://doaj.org/article/cac1997a64364844abf74f8df5037bf3Test |
| رقم الانضمام: | edsdoj.1997a64364844abf74f8df5037bf3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19910088 64364844 |
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| DOI: | 10.3329/bjp.v8i1.13485 |