دورية أكاديمية
أعرض في EDS

Differential expression and clinical significance of IGF2BP3 in peritoneal dialysate of patients with varying duration of peritoneal dialysis

التفاصيل البيبلوغرافية
العنوان: Differential expression and clinical significance of IGF2BP3 in peritoneal dialysate of patients with varying duration of peritoneal dialysis
المؤلفون: Xiaoqi Shao, Ling Yao, Jiao Fu, Mengmeng He, Pei Zhang
المصدر: Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Therapeutics. Pharmacology
LCC:Public aspects of medicine
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270
الوصف: Abstract This study aims to investigate the differential expression of insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in the peritoneal dialysate among patients with different durations of peritoneal dialysis and its association with the angiogenic marker vascular* endothelial growth factor (VEGF), the fibronectin (FN), and various clinical indicators. A cohort of 122 peritoneal dialysis patients was categorized into short‐term (≤1 year, n = 33), mid‐term (>1 and ≤5 years, n = 55), and long‐term (>5 years, n = 34) groups based on dialysis duration. We utilized enzyme‐linked immunosorbent assay (ELISA) and western blot assays to quantify the levels of IGF2BP3, VEGF, and FN in the dialysate. Our findings showed a progressive increase in IGF2BP3 levels with the duration of PD, with the long‐term group exhibiting significantly higher levels than both the short‐term and mid‐term groups (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1752-8062
1752-8054
العلاقة: https://doaj.org/toc/1752-8054Test; https://doaj.org/toc/1752-8062Test
DOI: 10.1111/cts.13774
الوصول الحر: https://doaj.org/article/18d86978ff344c82a43721067ccafe40Test
رقم الانضمام: edsdoj.18d86978ff344c82a43721067ccafe40
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17528062
17528054
DOI:10.1111/cts.13774