Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

التفاصيل البيبلوغرافية
العنوان:	Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3
المؤلفون:	Zhiyuan Zheng, Ya-nan Li, Shanfen Jia, Mengting Zhu, Lijuan Cao, Min Tao, Jingting Jiang, Shenghua Zhan, Yongjing Chen, Ping-Jin Gao, Weiguo Hu, Ying Wang, Changshun Shao, Yufang Shi
المصدر:	Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
بيانات النشر:	Nature Portfolio, 2021.
سنة النشر:	2021
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	The formation of the pre-metastatic niche enables the colonisation of disseminated cancer cells in distant organs. Here, the authors show that Th2 cytokines induce Complement 3 production in lung mesenchymal stromal cells, which recruits neutrophils and promotes the formation neutrophil extracellular traps, facilitating breast cancer cell metastasis to the lungs.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
العلاقة:	https://doaj.org/toc/2041-1723Test
DOI:	10.1038/s41467-021-26460-z
الوصول الحر:	https://doaj.org/article/156f0ce9dbfa4a79ac075c19ee86e1cdTest
رقم الانضمام:	edsdoj.156f0ce9dbfa4a79ac075c19ee86e1cd
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-021-26460-z