دورية أكاديمية
Prevalence and risk factors for diabetic peripheral neuropathy, neuropathic pain and foot ulceration in the Arabian Gulf region
| العنوان: | Prevalence and risk factors for diabetic peripheral neuropathy, neuropathic pain and foot ulceration in the Arabian Gulf region |
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| المؤلفون: | Georgios Ponirakis, Tarik Elhadd, Ebaa Al Ozairi, Imad Brema, Subitha Chinnaiyan, Etab Taghadom, Jumana Al Kandari, Rehab Al Wotayan, Abdulla Al Ozairi, Naji Aljohani, Wael AlMistehi, Nora Al Qahtani, Shawana Khan, Zeinab Dabbous, Mashhood A Siddique, Ioannis N Petropoulos, Adnan Khan, Hamad Almuhannadi, Khaled AE Ashawesh, Khaled M Dukhan, Ziyad R Mahfoud, Mahmoud A Zirie, Amin Jayyousi, Rayaz A Malik |
| المصدر: | Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1551-1559 (2022) |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | Diabetic foot ulceration, Diabetic peripheral neuropathy, Painful diabetic peripheral neuropathy, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | Abstract Aims/Introduction This study determined the prevalence and risk factors for diabetic peripheral neuropathy (DPN), painful DPN and diabetic foot ulceration (DFU) in patients with type 2 diabetes in secondary healthcare in Qatar, Kuwait and the Kingdom of Saudi Arabia. Materials and Methods Adults aged 18–85 years with type 2 diabetes were randomly enrolled from secondary healthcare, and underwent clinical and metabolic assessment. DPN was evaluated using vibration perception threshold and neuropathic symptoms and painful Diabetic Peripheral Neuropathy was evaluated using the Douleur Neuropathique 4 questionnaire. Results A total of 3,021 individuals were recruited between June 2017 and May 2019. The prevalence of DPN was 33.3%, of whom 52.2% were at risk of DFU and 53.6% were undiagnosed. The prevalence of painful DPN was 43.3%, of whom 54.3% were undiagnosed. DFU was present in 2.9%. The adjusted odds ratios for DPN and painful DPN were higher with increasing diabetes duration, obesity, poor glycemic control and hyperlipidemia, and lower with greater physical activity. The adjusted odds ratio for DFU was higher with the presence of DPN, severe loss of vibration perception, hypertension and vitamin D deficiency. Conclusions This is the largest study to date from the Middle East showing a high prevalence of undiagnosed DPN, painful DPN and those at risk of DFU in patients with type 2 diabetes, and identifies their respective risk factors. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2040-1124 2040-1116 |
| العلاقة: | https://doaj.org/toc/2040-1116Test; https://doaj.org/toc/2040-1124Test |
| DOI: | 10.1111/jdi.13815 |
| الوصول الحر: | https://doaj.org/article/10580d168cb947b3ac22d015e054b5eaTest |
| رقم الانضمام: | edsdoj.10580d168cb947b3ac22d015e054b5ea |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20401124 20401116 |
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| DOI: | 10.1111/jdi.13815 |