دورية أكاديمية
Thermal injury induces early blood vessel occlusion in a porcine model of brass comb burn
العنوان: | Thermal injury induces early blood vessel occlusion in a porcine model of brass comb burn |
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المؤلفون: | Jing Wang, Cheng Z. Wang, John R. Salsbury, Jianzi Zhang, Perenlei Enkhbaatar, David N. Herndon, Amina El Ayadi, Naseem H. Ansari |
المصدر: | Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) |
بيانات النشر: | Nature Portfolio, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Abstract Burn wound progression is an important determinant of patient morbidity and mortality after injury. In this study, we used the brass comb contact burn to determine burn wound vertical injury progression with a focus on blood vessel occlusion and endothelial cell death. Class A 3-month-old Yorkshire pigs received a brass comb contact burn. Burn wounds were sampled at 0, 30 min, 1, 2, 4, and 24 h. Hematoxylin Phloxin Saffron staining and vimentin immunostaining were performed to determine the depth of blood vessel occlusion and endothelial cell death, respectively. The depth of blood vessel occlusion increased by 30 min (p 0.05). The depth of endothelial cell death risen to a plateau at 30 min (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2045-2322 |
العلاقة: | https://doaj.org/toc/2045-2322Test |
DOI: | 10.1038/s41598-021-91874-0 |
الوصول الحر: | https://doaj.org/article/1028ae025be443d5adf3f624d995332dTest |
رقم الانضمام: | edsdoj.1028ae025be443d5adf3f624d995332d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20452322 |
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DOI: | 10.1038/s41598-021-91874-0 |