دورية أكاديمية
A comprehensive evaluation of adverse childhood experiences, social–emotional impairments, and neurodevelopmental disorders in cannabis-use disorder: Implications for clinical practice
| العنوان: | A comprehensive evaluation of adverse childhood experiences, social–emotional impairments, and neurodevelopmental disorders in cannabis-use disorder: Implications for clinical practice |
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| المؤلفون: | Giada Trovini, Emanuela Amici, Piergiorgio Bauco, Marta Matrone, Ginevra Lombardozzi, Valeria Giovanetti, Georgios D. Kotzalidis, Sergio De Filippis |
| المصدر: | European Psychiatry, Vol 66 (2023) |
| بيانات النشر: | Cambridge University Press, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Psychiatry |
| مصطلحات موضوعية: | adverse childhood experiences, cannabis, history of pre-onset conditions, mental disorders, substance-use disorders, Psychiatry, RC435-571 |
| الوصف: | Abstract Background Adverse childhood experiences (ACEs), social–emotional impairments (SEIs), and neurodevelopmental disorders (NDs) are frequent in psychiatric disorders, including substance-use disorders. We aimed to determine the prevalence of ACE, SEI, or ND in individuals with cannabis-use disorder (CUD). We compared individuals with preCUD-onset ACE, SEI, or ND to those without. Methods We crosssectionally studied 323 inpatients or outpatients with a history of past or current CUD, aged 12–35 years (mean age 22.94 ± 4.79), 64.5% of whom were male. The sample was divided into two groups: the non-premorbid (N = 52) and the premorbid ACE/SEI/ND group (N = 271). Within the premorbid group, further subgroups were based on ACEs, SEI, and NDs. We also analyzed other substance use and psychiatric symptoms/diagnoses based on the non-premorbid-premorbid dichotomy in the CUD sample. Results Pre-CUD ACE-SEI-ND had higher prevalence of bipolar, schizoaffective, borderline personality, and attention-deficit/hyperactivity disorders, and a history of agitation, hallucinations, and self-injury. The ACE group had higher rates of agitation, depression, delusions, hallucinations, eating disorders, and use of cocaine, amphetamines, and hallucinogens than the SEI or ND. Patients in the premorbid group initiated cannabis use at an earlier age, experienced the first comorbid psychiatric episode earlier, and were hospitalized earlier than those in the non- premorbid ACE-SEI-ND group. Conclusions PreCUD-onset ACE, SEI, or ND conditions in individuals with CUDare linked to earlier onset of comorbid mental illness. Furthermore, ACEs contribute to significant and potentially severe clinical symptoms, as well as the use of substances other than cannabis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0924-9338 1778-3585 |
| العلاقة: | https://www.cambridge.org/core/product/identifier/S0924933823024367/type/journal_articleTest; https://doaj.org/toc/0924-9338Test; https://doaj.org/toc/1778-3585Test |
| DOI: | 10.1192/j.eurpsy.2023.2436 |
| الوصول الحر: | https://doaj.org/article/0bc5e973f96b4dd6b172d8a5755e092eTest |
| رقم الانضمام: | edsdoj.0bc5e973f96b4dd6b172d8a5755e092e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09249338 17783585 |
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| DOI: | 10.1192/j.eurpsy.2023.2436 |