التفاصيل البيبلوغرافية
العنوان:
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices
المؤلفون:
Pradeep Natarajan , Akhil Pampana , Sarah E. Graham , Sanni E. Ruotsalainen , James A. Perry , Paul S. de Vries , Jai G. Broome , James P. Pirruccello , Michael C. Honigberg , Krishna Aragam , Brooke Wolford , Jennifer A. Brody , Lucinda Antonacci-Fulton , Moscati Arden , Stella Aslibekyan , Themistocles L. Assimes , Christie M. Ballantyne , Lawrence F. Bielak , Joshua C. Bis , Brian E. Cade , Ron Do , Harsha Doddapaneni , Leslie S. Emery , Yi-Jen Hung , Marguerite R. Irvin , Alyna T. Khan , Leslie Lange , Jiwon Lee , Rozenn N. Lemaitre , Lisa W. Martin , Ginger Metcalf , May E. Montasser , Jee-Young Moon , Donna Muzny , Jeffrey R. O’Connell , Nicholette D. Palmer , Juan M. Peralta , Patricia A. Peyser , Adrienne M. Stilp , Michael Tsai , Fei Fei Wang , Daniel E. Weeks , Lisa R. Yanek , James G. Wilson , Goncalo Abecasis , Donna K. Arnett , Lewis C. Becker , John Blangero , Eric Boerwinkle , Donald W. Bowden , Yi-Cheng Chang , Yii-Der I. Chen , Won Jung Choi , Adolfo Correa , Joanne E. Curran , Mark J. Daly , Susan K. Dutcher , Patrick T. Ellinor , Myriam Fornage , Barry I. Freedman , Stacey Gabriel , Soren Germer , Richard A. Gibbs , Jiang He , Kristian Hveem , Gail P. Jarvik , Robert C. Kaplan , Sharon L. R. Kardia , Eimear Kenny , Ryan W. Kim , Charles Kooperberg , Cathy C. Laurie , Seonwook Lee , Don M. Lloyd-Jones , Ruth J. F. Loos , Steven A. Lubitz , Rasika A. Mathias , Karine A. Viaud Martinez , Stephen T. McGarvey , Braxton D. Mitchell , Deborah A. Nickerson , Kari E. North , Aarno Palotie , Cheol Joo Park , Bruce M. Psaty , D. C. Rao , Susan Redline , Alexander P. Reiner , Daekwan Seo , Jeong-Sun Seo , Albert V. Smith , Russell P. Tracy , Ramachandran S. Vasan , Sekar Kathiresan , L. Adrienne Cupples , Jerome I. Rotter , Alanna C. Morrison , Stephen S. Rich , Samuli Ripatti , Cristen Willer , NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium , FinnGen , Gina M. Peloso
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq23 locus with lipid changes and reduced risk of CHD and diabetes mellitus.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-021-22339-1
الوصول الحر:
https://doaj.org/article/09cb57a2d8544b5e803b374995f412e4Test
رقم الانضمام:
edsdoj.09cb57a2d8544b5e803b374995f412e4
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