التفاصيل البيبلوغرافية
العنوان:
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
المؤلفون:
Dario Zimmerli , Chiara S. Brambillasca , Francien Talens , Jinhyuk Bhin , Renske Linstra , Lou Romanens , Arkajyoti Bhattacharya , Stacey E. P. Joosten , Ana Moises Da Silva , Nuno Padrao , Max D. Wellenstein , Kelly Kersten , Mart de Boo , Maurits Roorda , Linda Henneman , Roebi de Bruijn , Stefano Annunziato , Eline van der Burg , Anne Paulien Drenth , Catrin Lutz , Theresa Endres , Marieke van de Ven , Martin Eilers , Lodewyk Wessels , Karin E. de Visser , Wilbert Zwart , Rudolf S. N. Fehrmann , Marcel A. T. M. van Vugt , Jos Jonkers
المصدر:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
بيانات النشر:
Nature Portfolio, 2022.
سنة النشر:
2022
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Tripe-negative breast cancers poorly respond to immune checkpoint inhibition therapy, due to their immune-hostile tumour microenvironment. Authors here show that the oncogene MYC plays a pivotal role in suppressing anti-tumour immunity via directly regulating the transcription of interferon signalling genes.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-022-34000-6
الوصول الحر:
https://doaj.org/article/07f7321be51a4bf993332239abb08b2bTest
رقم الانضمام:
edsdoj.07f7321be51a4bf993332239abb08b2b
قاعدة البيانات:
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