دورية أكاديمية
Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study
| العنوان: | Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study |
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| المؤلفون: | Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom, Andrew Gallagher |
| المصدر: | Nutrition & Metabolism, Vol 18, Iss 1, Pp 1-9 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: | Mulberry leaf extract, Glycaemic response, Insulinaemic response, 1-deoxynojirimycin, Lifestyle changes, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: | Abstract Background There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycaemia. Significant health-related lifestyle changes are often difficult to implement and functional ingredients that can reduce glycaemic and insulaemic responses may help at risk populations. The aim of this study was to investigate whether a mulberry leaf extract could lower the glycaemic and insulinaemic responses to 75 g sucrose in healthy individuals. Methods A double-blind, randomised, placebo-controlled, crossover design trial was conducted by the Oxford Brookes Centre for Nutrition and Health. Thirty-eight participants were recruited into the trial and, after an overnight fast, were given 75 g sucrose + white mulberry leaf extract, or 75 g sucrose alone. Capillary blood samples were collected at 15-min intervals in the first hour and at 30-min intervals over the second hour to determine glucose and plasma insulin levels. Data analysis was conducted using a paired samples T test or a Wilcoxon signed rank test. Results The addition of mulberry leaf extract to sucrose resulted in a significantly lower glycaemic response and insulinaemic response compared to a matched placebo (sucrose alone). The change in blood glucose measurements were significantly lower at 15 min (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1743-7075 |
| العلاقة: | https://doaj.org/toc/1743-7075Test |
| DOI: | 10.1186/s12986-021-00571-2 |
| الوصول الحر: | https://doaj.org/article/c032e2b729ec4c679317a751ef3711edTest |
| رقم الانضمام: | edsdoj.032e2b729ec4c679317a751ef3711ed |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17437075 |
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| DOI: | 10.1186/s12986-021-00571-2 |