دورية أكاديمية
Hepatic Proteins and Inflammatory Markers in Rheumatoid Arthritis Patients
| العنوان: | Hepatic Proteins and Inflammatory Markers in Rheumatoid Arthritis Patients |
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| المؤلفون: | Manel BEN-HADJ-MOHAMED, Souhir KHELIL, Mokhles BEN DBIBIS, Latifa KHLIFI, Hend CHAHED, Salima FERCHICHI, Elyes BOUAJINA, Abdelhédi MILED |
| المصدر: | Iranian Journal of Public Health, Vol 46, Iss 8 (2017) |
| بيانات النشر: | Tehran University of Medical Sciences, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Hepatic proteins, Inflammation, Iron metabolism, Rheumatoid arthritis, Public aspects of medicine, RA1-1270 |
| الوصف: | Background: Rheumatoid arthritis is an autoimmune inflammatory rheumatic disease that causes chronic synovial inflammation eventually leading to joint destruction and disability. The aim of this study was to determine the variations of hepatic proteins, myeloperoxidase, and iron in rheumatoid arthritis Tunisian patients and their implications in inflammation and in iron metabolism. Methods: Overall, 172 patients from the Rheumatology Department of the University Hospital “Farhat Hached”, Sousse-Tunisia between 2011 and 2012, with rheumatoid arthritis (97.1% women, average age: 48±13 yr) and 147 healthy volunteers (70.1% women, average age: 46± 7 yr) were included in this study. Serum hepatic proteins (high-sensitive C-reactive protein, ceruloplasmin, albumin, transferrin, α-1-acid glycoprotein and haptoglobin) were assessed by immunoturbidimetry (COBAS INTEGRA 400, Roche) and ferritin was measured by a microparticulate immunoenzymatic technic (AxSYM, ABBOTT, Germany), Plasma myeloperoxidase was determined by Enzyme-Linked Immunosorbent Assay. Serum iron was measured according to a colorimetric method at 595 nm (CX9-BECKMANN Coulter-Fuller-Ton, CA). Results: Significantly higher levels of high-sensitive C-reactive protein, α-1-acid glycoprotein, Haptoglobin and myeloperoxidase in patients compared to controls (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2251-6085 2251-6093 |
| العلاقة: | https://ijph.tums.ac.ir/index.php/ijph/article/view/10606Test; https://doaj.org/toc/2251-6085Test; https://doaj.org/toc/2251-6093Test |
| الوصول الحر: | https://doaj.org/article/029f744532cd4fbf99e63fbc55ab7295Test |
| رقم الانضمام: | edsdoj.029f744532cd4fbf99e63fbc55ab7295 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22516085 22516093 |
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