التفاصيل البيبلوغرافية
| العنوان: |
Individualised growth charts for preterm infants based on a cohort with good neurodevelopment |
| المؤلفون: |
Young, Aneurin, Beattie, Robert M., Johnson, Mark John |
| سنة النشر: |
2024 |
| المجموعة: |
University of Southampton: e-Prints Soton |
| الوصف: |
Background and aims: current growth charts for preterm infants, based on cross-sectional birthweight data, do not reflect normal early postnatal growth patterns. Faster weight gain during early postnatal life is associated with improved neurodevelopment. This study aimed to generate personalised growth charts which reflect postnatal growth of infants with good neurodevelopment. Methods: data for infants born before 32 weeks gestation between 2014 and 2018 were provided by the UK National Neonatal Research Database. Infants with physician-described development “normal or less than three months delay” were selected. LMS growth charts for weight gain were generated using the gamlss package for R and taking day of life as the independent variable. A web app was created to generate personalised growth charts for infants and plot their growth. Results: complete data were available for 14,120 infants, of whom 9,128 had normal development. Early growth of preterm infants was associated with a higher chance of normal development after adjustment for gestation, SGA, sex, Apgar score and post-discharge growth (p<0.01). The weight gain pattern for extremely preterm infants was different to the pattern for more mature infants, so separate LMS growth models were generated. A personalised growth web app was made available at www.bit.ly/preterm-plotter (example pictured). Conclusions: the association between faster early weight gain and improved neurodevelopment was confirmed. A web app is provided so that weight gain of infants can be compared with preterm infants with good neurodevelopment, with plausible postnatal growth patterns. Future work will use infants without major neonatal morbidities and provide charts for other measurements. |
| نوع الوثيقة: |
conference object |
| اللغة: |
English |
| العلاقة: |
Young, Aneurin, Beattie, Robert M. and Johnson, Mark John (2024) Individualised growth charts for preterm infants based on a cohort with good neurodevelopment. European Society of Paediatric Gastroenterology, Hepatology and Nutrition 56th Annual Meeting, , Milan, Italy. 15 - 18 May 2024. |
| الإتاحة: |
https://eprints.soton.ac.uk/490691Test/ |
| رقم الانضمام: |
edsbas.FFF64240 |
| قاعدة البيانات: |
BASE |
