دورية أكاديمية

Cardiac sympathetic nerve activity trends after renal denervation in heart failure with preserved ejection fraction

التفاصيل البيبلوغرافية
العنوان: Cardiac sympathetic nerve activity trends after renal denervation in heart failure with preserved ejection fraction
المؤلفون: Shiraki, Tatsuya, Mizuno, Hiroya, Kishi, Takuya, Asakura, Masanori, Asanoi, Hidetsugu, Yasumura, Yoshio, Sakata, Yasushi
المصدر: ESC Heart Failure ; ISSN 2055-5822 2055-5822
بيانات النشر: Wiley
سنة النشر: 2024
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: This case report describes the application of ultrasound renal denervation (uRDN) using the Paradise System in a patient with heart failure with preserved ejection fraction. Initially, the cardiac sympathetic nerve activity of the patient exhibited a late heart/mediastinum (H/M) ratio of 2.00 and a washout rate of 66.0% by cardiac iodine‐123 metaiodobenzylguanidine ( 123 I‐MIBG) scintigraphy. Subsequently, the patient underwent transfemoral uRDN targeting the left, right upper, and right lower renal arteries. At the 6 month follow‐up, no significant change was observed in 123 I‐MIBG findings; however, the estimated stressed blood volume (eSBV) decreased from 1722 to 1029 mL/70 kg. At 18 months, 123 I‐MIBG findings improved, with the late H/M ratio reaching 2.76 and the washout rate decreasing to 43.1%. This case report highlights the potential of uRDN in reducing eSBV within 6 months and subsequently improving cardiac sympathetic nerve activity at the 18 month follow‐up.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1002/ehf2.14770
الإتاحة: https://doi.org/10.1002/ehf2.14770Test
حقوق: http://creativecommons.org/licenses/by-nc/4.0Test/
رقم الانضمام: edsbas.FFEAD74B
قاعدة البيانات: BASE