دورية أكاديمية
Experimental Coxiella burnetii infection in pregnant goats: excretion routes
| العنوان: | Experimental Coxiella burnetii infection in pregnant goats: excretion routes |
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| المؤلفون: | Bouvery, Nathalie, Souriau, Armel, Lechopier, Patrick, Rodolakis, Annie |
| المصدر: | ISSN: 0928-4249. |
| بيانات النشر: | HAL CCSD BioMed Central |
| سنة النشر: | 2003 |
| المجموعة: | Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
| مصطلحات موضوعية: | Coxiella burnetii, goat, experimental infection, abortion, shedding, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.BA]Life Sciences [q-bio]/Animal biology |
| الوصف: | International audience ; Q fever is a widespread zoonosis caused by Coxiella burnetii. Infected animals, shedding bacteria by different routes, constitute contamination sources for humans and the environment. To study Coxiella excretion, pregnant goats were inoculated by the subcutaneous route in a site localized just in front of the shoulder at 90 days of gestation with 3 doses of bacteria (10$^{8}$, 10$^{6}$ or 10$^{4}$ I.D.). All the goats aborted whatever the dose used. Coxiella were found by PCR and immunofluorescence tests in all placentas and in several organs of at least one fetus per goat. At abortion, all the goats excreted bacteria in vaginal discharges up to 14 days and in milk samples up to 52 days. A few goats excreted Coxiella in their feces before abortion, and all goats, excreted bacteria in their feces after abortion. Antibody titers against Coxiella increased from 21 days post inoculation to the end of the experiment. For a Q fever diagnostic, detection by PCR and immunofluorescence tests of Coxiella in parturition products and vaginal secretions at abortion should be preferred to serological tests. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-00902757; https://hal.archives-ouvertes.fr/hal-00902757Test; https://hal.archives-ouvertes.fr/hal-00902757/documentTest; https://hal.archives-ouvertes.fr/hal-00902757/file/hal-00902757.pdfTest; PRODINRA: 145876; WOS: ISI:000184713700006 |
| DOI: | 10.1051/vetres:2003017 |
| الإتاحة: | https://doi.org/10.1051/vetres:2003017Test https://hal.archives-ouvertes.fr/hal-00902757Test https://hal.archives-ouvertes.fr/hal-00902757/documentTest https://hal.archives-ouvertes.fr/hal-00902757/file/hal-00902757.pdfTest |
| حقوق: | http://hal.archives-ouvertes.fr/licences/copyrightTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.FF1A8356 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1051/vetres:2003017 |
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