دورية أكاديمية
Simulations.
| العنوان: | Simulations. |
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| المؤلفون: | Massimo Attanasio, Fabio Aiello, Fabio Tinè |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Cancer, Science Policy, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, whereas preliminary quantitative, several checklists describing, four stages aimed, darling test applied, removing unbalanced trials, combinability &# 8221, analysis , identify unbalanced trials, unbalanced trials, &# 8220, |
| الوصف: | In meta-analysis literature, there are several checklists describing the procedures necessary to evaluate studies from a qualitative point of view, whereas preliminary quantitative and statistical investigations on the “combinability” of trials have been neglected. Covariate balance is an important prerequisite to conduct meta-analysis. We propose a method to identify unbalanced trials with respect to a set of covariates, in presence of covariate imbalance, namely when the randomized controlled trials generate a meta-sample that cannot satisfy the requisite of randomization/combinability in meta-analysis. The method is able to identify the unbalanced trials, through four stages aimed at achieving combinability. The studies responsible for the imbalance are identified, and then they can be eliminated. The proposed procedure is simple and relies on the combined Anderson-Darling test applied to the Empirical Cumulative Distribution Functions of both experimental and control meta-arms. To illustrate the method in practice, two datasets from well-known meta-analyses in the literature are used. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/Simulations_/24841738Test |
| DOI: | 10.1371/journal.pone.0295332.s001 |
| الإتاحة: | https://doi.org/10.1371/journal.pone.0295332.s001Test https://figshare.com/articles/journal_contribution/Simulations_/24841738Test |
| حقوق: | CC BY 4.0 |
| رقم الانضمام: | edsbas.FD5C0B48 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1371/journal.pone.0295332.s001 |
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