دورية أكاديمية

All-cause mortality and estimated renal function in type 2 diabetes mellitus outpatients: Is there a relationship with the equation used?

التفاصيل البيبلوغرافية
العنوان: All-cause mortality and estimated renal function in type 2 diabetes mellitus outpatients: Is there a relationship with the equation used?
المؤلفون: Fabbian, Fabio, De Giorgi, Alfredo, Monesi, Marcello, Pala, Marco, Tiseo, Ruana, Misurati, Elisa, Parisi, Claudia, Volpi, Riccardo, Graziani, Roberto, Mikhailidis, Dimitri P, Manfredini, Roberto
المصدر: Diabetes and Vascular Disease Research ; volume 12, issue 1, page 46-52 ; ISSN 1479-1641 1752-8984
بيانات النشر: SAGE Publications
سنة النشر: 2014
مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, Internal Medicine
الوصف: Background: We investigated the relationship between serum creatinine (SCr) and estimated glomerular filtration rate (eGFR), evaluated by different formulae, and all-cause mortality (ACM) in type 2 diabetes mellitus (T2DM) outpatients. Methods: This observational cohort study considered 1365 T2DM outpatients, who had been followed up for a period of up to 11 years. eGFR was estimated using several equations. Results: Seventy subjects (5.1%) died after a follow-up of 9.8 ± 3 years. Univariate analysis showed that diagnosis of nephropathy (odds ratio (OR): 2.554, 95% confidence interval (CI): 1.616–4.038, p < 0.001) and microvascular complications (OR: 2.281, 95% CI: 1.449–3.593, p < 0.001) were associated with ACM. Receiving operating characteristic (ROC) curves showed that the areas under the curve for ACM were similar using the different eGFR equations. eGFR values were predictors of ACM, and the hazard ratios (HRs) of the different equations for eGFR estimation were similar. Conclusion: In our cohort of T2DM outpatients, different eGFR equations perform similarly in predicting ACM, whereas SCr did not.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/1479164114552656
الإتاحة: https://doi.org/10.1177/1479164114552656Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.FD04399A
قاعدة البيانات: BASE