دورية أكاديمية
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia
| العنوان: | United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia |
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| المؤلفون: | Wauters L., Dickman R., Drug V., Mulak A., Serra J., Enck P., Tack J., Accarino A., Barbara G., Bor S., Coffin B., Corsetti M., De Schepper H., Dumitrascu D., Farmer A., Gourcerol G., Hauser G., Hausken T., Karamanolis G., Keszthelyi D., Malagelada C., Milosavljevic T., Muris J., O'Morain C., Papathanasopoulos A., Pohl D., Rumyantseva D., Sarnelli G., Savarino E., Schol J., Sheptulin A., Smet A., Stengel A., Storonova O., Storr M., Tornblom H., Vanuytsel T., Velosa M., Waluga M., Zarate N., Zerbib F. |
| المساهمون: | Wauters L., Dickman R., Drug V., Mulak A., Serra J., Enck P., Tack J., Accarino A., Barbara G., Bor S., Coffin B., Corsetti M., De Schepper H., Dumitrascu D., Farmer A., Gourcerol G., Hauser G., Hausken T., Karamanolis G., Keszthelyi D., Malagelada C., Milosavljevic T., Muris J., O'Morain C., Papathanasopoulos A., Pohl D., Rumyantseva D., Sarnelli G., Savarino E., Schol J., Sheptulin A., Smet A., Stengel A., Storonova O., Storr M., Tornblom H., Vanuytsel T., Velosa M., Waluga M., Zarate N., Zerbib F. |
| سنة النشر: | 2021 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | consensu, endoscopy, evidence-based medicine, functional dyspepsia, proton pump inhibitor, Abdominal Pain, Gastrointestinal, Europe, Female, Gastroenterology, Helicobacter Infection, Helicobacter pylori, Human, Male, Neurology, Postprandial Period, Quality of Life, Risk Factor, Satiation, Sex Factor, Symptom Assessment, Delphi Technique, Dyspepsia, Societies, Medical |
| الوصف: | Background: Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and prognosis. Methods: A Delphi consensus was initiated with 41 experts from 22 European countries who conducted a literature summary and voting process on 87 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation (GRADE) criteria. Consensus (defined as >80% agreement) was reached for 36 statements. Results: The panel agreed with the definition in terms of its cardinal symptoms (early satiation, postprandial fullness, epigastric pain, and epigastric burning), its subdivision into epigastric pain syndrome and postprandial distress syndrome, and the presence of accessory symptoms (upper abdominal bloating, nausea, belching), and overlapping conditions. Also, well accepted are the female predominance of FD, its impact on quality of life and health costs, and acute gastrointestinal infections, and anxiety as risk factors. In terms of pathophysiological mechanisms, the consensus supports a role for impaired gastric accommodation, delayed gastric emptying, hypersensitivity to gastric distention, Helicobacter pylori infection, and altered central processing of signals from the gastroduodenal region. There is consensus that endoscopy is mandatory for establishing a firm diagnosis of FD, but that in primary care, patients without alarm symptoms or risk factors can be managed without endoscopy. There is consensus that H. pylori status should be determined in every patient with dyspeptic symptoms and H. pylori positive patients should receive eradication therapy. Also, proton pump inhibitor therapy is considered an effective therapy for FD, but no other treatment approach reached a consensus. The long-term prognosis and life expectancy are favorable. Conclusions and Inferences: A multinational group of European ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33939891; info:eu-repo/semantics/altIdentifier/wos/WOS:000646335800003; volume:9; issue:3; firstpage:307; lastpage:331; numberofpages:25; journal:UNITED EUROPEAN GASTROENTEROLOGY JOURNAL; https://hdl.handle.net/11585/856325Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85105081658 |
| DOI: | 10.1002/ueg2.12061 |
| الإتاحة: | https://doi.org/10.1002/ueg2.12061Test https://hdl.handle.net/11585/856325Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.FCC5D639 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ueg2.12061 |
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