دورية أكاديمية
Pictorial information about subclinical atherosclerosis reduces the CVD risk: Results from the VIPVIZA RCT
| العنوان: | Pictorial information about subclinical atherosclerosis reduces the CVD risk: Results from the VIPVIZA RCT |
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| المؤلفون: | Bengtsson, A, Norberg, M, Ng, N, Carlberg, B, Gronlund, C, Hultdin, J, Lindahl, B, Nordin, S, Nyman, E, Wennberg, P, Wester, P, Naslund, U |
| المصدر: | European Journal of Preventive Cardiology ; volume 28, issue Supplement_1 ; ISSN 2047-4873 2047-4881 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cardiology and Cardiovascular Medicine, Epidemiology |
| الوصف: | Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Region Västerbotten and the Swedish Research Council Background The VIPVIZA trial has previously shown beneficial effects on cardiovascular disease (CVD) risk scores 1 year after sending pictorial information of carotid ultrasound imaging (Picture 1) to individuals and their physicians Purpose To investigate whether the beneficial effects on CVD-risk observed at 1-year were sustained over three years Methods VIPVIZA is a pragmatic prospective open-label randomized controlled trial with blinded evaluators performed within a CVD prevention programme integrated in the regular primary health care in Västerbotten County, Sweden. Individuals aged 40, 50 or 60 years old with one CVD risk factor were enrolled and randomised 1:1 to intervention (n = 1749, pictorial information about subclinical atherosclerosis provided to participants and physicians, Picture 1) or control group(n = 1783, no information to participants or physicians). Intervention participants also recieved a follow-up phone call and the corresponding physicians written guideline-based information about the clinical significance of carotid ultrasound results. Participants were examined at baseline (2013-2016), after one and at three years Results A significant beneficial effect on cardiovascular risk was observed at the 3-year follow-up; Framingham Risk Score (FRS) was 13.38 for the intervention group and 14.08 for the control group(p = 0.047) and SCORE was 1.69 vs. 1.82(p = 0.022) respectively. The 3-year results adjusted for sex and educational level showed significant differences between the intervention and control group in FRS, SCORE, P-Total-Cholesterol, P-LDL-Cholesterol and waist circumference in favour of the intervention group. Analysis by sex showed difference in differences(DID) in FRS for men -1.19(95% CI -2.01 to -0.37) and -0.50(95% CI -0.93 to -0.07) for women and in SCORE for men -0.20(95% CI -0.33 to -0.06) and -0.08 (95% CI -0.13 to ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/eurjpc/zwab061.248 |
| الإتاحة: | https://doi.org/10.1093/eurjpc/zwab061.248Test http://academic.oup.com/eurjpc/article-pdf/28/Supplement_1/zwab061.248/37908984/zwab061.248.pdfTest |
| حقوق: | https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_modelTest |
| رقم الانضمام: | edsbas.F960664D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/eurjpc/zwab061.248 |
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