Innate Immune Sensing by Cells of the Adaptive Immune System

التفاصيل البيبلوغرافية
العنوان:	Innate Immune Sensing by Cells of the Adaptive Immune System
المؤلفون:	Stogerer, Tanja, Stäger, Simona
سنة النشر:	2020
المجموعة:	Institut national de la recherche scientifique, Québec: Espace INRS
مصطلحات موضوعية:	B and T cells, DAMPs, PRRs, TLRs, adaptive immunity, chronic infections
الوصف:	Sensing of microbes or of danger signals has mainly been attributed to myeloid innate immune cells. However, T and B cells also express functional pattern recognition receptors (PRRs). In these cells, PRRs mediate signaling cascades that result in different functions depending on the cell's activation and/or differentiation status, on the environment, and on the ligand/agonist. Some of these functions are beneficial for the host; however, some are detrimental and are exploited by pathogens to establish persistent infections. In this review, we summarize the available literature on innate immune sensing by cells of the adaptive immune system and discuss possible implications for chronic infections.
نوع الوثيقة:	article in journal/newspaper
وصف الملف:	application/pdf
اللغة:	English
العلاقة:	https://espace.inrs.ca/id/eprint/11692/1/Innate%20Immune%20Sensing%20by%20Cells%20of%20the%20Adaptive%20Immune%20System-stager%202020.pdfTest; Stogerer, Tanja et Stäger, Simona orcid:0000-0001-5508-9565 (2020). Innate Immune Sensing by Cells of the Adaptive Immune System Frontiers in Immunology , vol. 11 , nº 1081. p. 1-11. DOI:10.3389/fimmu.2020.01081 .
DOI:	10.3389/fimmu.2020.01081
الإتاحة:	https://doi.org/10.3389/fimmu.2020.01081Test https://espace.inrs.ca/id/eprint/11692Test/ https://espace.inrs.ca/id/eprint/11692/1/Innate%20Immune%20Sensing%20by%20Cells%20of%20the%20Adaptive%20Immune%20System-stager%202020.pdfTest https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274159Test/
حقوق:	cc_by_4
رقم الانضمام:	edsbas.F726457A
قاعدة البيانات:	BASE

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الوصف
DOI:	10.3389/fimmu.2020.01081