التفاصيل البيبلوغرافية
| العنوان: |
An international review of the characteristics of viral nucleic acid‐amplification testing (NAT) reveals a trend towards the use of smaller pool sizes and individual donation NAT |
| المؤلفون: |
Faddy, Helen M., Osiowy, Carla, Custer, Brian, Busch, Michael, Stramer, Susan L., Dean, Melinda M., Acutt, Jessika, Viennet, Elvina, van de Laar, Thijs, Tsoi, Wai‐Chiu, Styles, Claire, Kiely, Phil, Margaritis, Angelo, Kwon, So‐Yong, Qiu, Yan, Deng, Xuelian, Lewin, Antoine, Jørgensen, Signe Winther, Erikstrup, Christian, Juhl, David, Sauleda, Silvia, Camacho Rodriguez, Bernardo Armando, Soto Coral, Lisbeth Jennifer Catherine, Gaviria García, Paula Andrea, Oota, Sineenart, O'Brien, Sheila F., Wendel, Silvano, Castro, Emma, Navarro Pérez, Laura, Harvala, Heli, Davison, Katy, Reynolds, Claire, Jarvis, Lisa, Grabarczyk, Piotr, Kopacz, Aneta, Łętowska, Magdalena, O'Flaherty, Niamh, Young, Fiona, Williams, Padraig, Burke, Lisa, Chua, Sze Sze, Muylaert, An, Page, Isabel, Jones, Ann, Niederhauser, Christoph, Vermeulen, Marion, Laperche, Syria, Gallian, Pierre, Satake, Masahiro, Addas‐Carvalho, Marcelo |
| المصدر: |
Vox Sanguinis ; ISSN 0042-9007 1423-0410 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2024 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Background and Objectives Nucleic acid‐amplification testing (NAT) is used for screening blood donations/donors for blood‐borne viruses. We reviewed global viral NAT characteristics and NAT‐yield confirmatory testing used by blood operators. Materials and Methods NAT characteristics and NAT‐yield confirmatory testing used during 2019 was surveyed internationally by the International Society of Blood Transfusion Working Party Transfusion‐Transmitted Infectious Diseases. Reported characteristics are presented herein. Results NAT was mainly performed under government mandate. Human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) NAT was performed on all donors and donation types, while selective testing was reported for West Nile virus, hepatitis E virus (HEV), and Zika virus. Individual donation NAT was used for HIV, HCV and HBV by ~50% of responders, while HEV was screened in mini‐pools by 83% of responders performing HEV NAT. Confirmatory testing for NAT‐yield samples was generally performed by NAT on a sample from the same donation or by NAT and serology on samples from the same donation and a follow‐up sample. Conclusion In the last decade, there has been a trend towards use of smaller pool sizes or individual donation NAT. We captured characteristics of NAT internationally in 2019 and provide insights into confirmatory testing approaches used for NAT‐yields, potentially benefitting blood operators seeking to implement NAT. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/vox.13617 |
| الإتاحة: |
https://doi.org/10.1111/vox.13617Test |
| حقوق: |
http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: |
edsbas.F41C51CA |
| قاعدة البيانات: |
BASE |
