التفاصيل البيبلوغرافية
| العنوان: |
Evolving therapeutic landscape of diffuse large B-cell lymphoma: challenges and aspirations |
| المؤلفون: |
Chan, Jason Yongsheng, Somasundaram, Nagavalli, Grigoropoulos, Nicholas, Lim, Francesca, Poon, Michelle Limei, Jeyasekharan, Anand, Yeoh, Kheng Wei, Tan, Daryl, Lenz, Georg, Ong, Choon Kiat, Lim, Soon Thye |
| المساهمون: |
Singapore Ministry of Health’s National Medical Research Council Research Transition Award, Singapore Ministry of Health’s National Medical Research Council Collaborative Centre Grant, Tanoto Foundation Professorship in Medical Oncology, New Century Foundation Limited, Ling Foundation, Singapore Ministry of Health’s National Medical Research Council Large Collaborative Grant |
| المصدر: |
Discover Oncology ; volume 14, issue 1 ; ISSN 2730-6011 |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Cancer Research, Endocrine and Autonomic Systems, Endocrinology, Oncology, Endocrinology, Diabetes and Metabolism |
| الوصف: |
Diffuse large B-cell lymphoma (DLBCL) represents the commonest subtype of non-Hodgkin lymphoma and encompasses a group of diverse disease entities, each harboring unique molecular and clinico-pathological features. The understanding of the molecular landscape of DLBCL has improved significantly over the past decade, highlighting unique genomic subtypes with implications on targeted therapy. At the same time, several new treatment modalities have been recently approved both in the frontline and relapsed settings, ending a dearth of negative clinical trials that plagued the past decade. Despite that, in the real-world setting, issues like drug accessibility, reimbursement policies, physician and patient preference, as well as questions regarding optimal sequencing of treatment options present difficulties and challenges in day-to-day oncology practice. Here, we review the recent advances in the therapeutic armamentarium of DLBCL and discuss implications on the practice landscape, with a particular emphasis on the context of the healthcare system in Singapore. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s12672-023-00754-8 |
| DOI: |
10.1007/s12672-023-00754-8.pdf |
| DOI: |
10.1007/s12672-023-00754-8/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s12672-023-00754-8Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.F0E12755 |
| قاعدة البيانات: |
BASE |
