دورية أكاديمية
Rate, correlates and outcomes of repeat pregnancy in HIV-infected women
| العنوان: | Rate, correlates and outcomes of repeat pregnancy in HIV-infected women |
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| المؤلفون: | Floridia M., Tamburrini E., Masuelli G., Martinelli P., Spinillo A., Liuzzi G., Vimercati A., Alberico S., Maccabruni A., Pinnetti C., Frisina V., Dalzero S., Ravizza M., Mori F., Ortolani P., dalle Nogare E. R., Di Lorenzo F., Sterrantino G., Meli M., Polemi S., Nocentini J., Baldini M., Montorzi G., Mazzetti M., Rogasi P., Borchi B., Vichi F., Del Pin B., Pinter E., Anzalone E., Marocco R., Mastroianni C., Mercurio V. S., Carocci A., Grilli E., Zaramella M., Mariani B., Natalini Raponi G., Guaraldi G., Nardini G., Stentarelli C., Beghetto B., Degli Antoni A. M., Molinari A., Crisalli M. P., Donisi A., Piepoli M., Cerri V., Zuccotti G., Giacomet V., Coletto S., Di Nello F., Madia C., Placido G., Vivarelli A., Castelli P., Savalli F., Portelli V., Sabbatini F., Francisci D., Bernini L., Grossi P., Rizzi L., Maso G., Airoud M., Soppelsa G., Meloni A., Dedoni M., Cuboni C., Ortu F., Piano P., Citernesi A., Bordoni Vicini I., Luzi K., Roccio M., Miccolis A., De Gennaro A., Guerra B., Cervi F., Simonazzi G., Margarito E., Capretti M. G., Marsico C., Faldella G., Sansone M., Agangi A., Capone A., Maruotti M., Tibaldi C., Trentini L., Todros T., Cetin I., Brambilla T., Savasi V., Personeni C., Giaquinto C., Fiscon M., Rubino E., Bucceri A., Matrone R., Scaravelli G., Genovese O., Cafforio C., Tozzi V., Massetti P., Casadei A. M., Cavaliere A. F., Cellini M., Castelli Gattinara G., Marconi A. M., Sacchi V., Ierardi M., Polizzi C., Mattei A., Pirillo M. F., Amici R., Galluzzo C. M., Donnini S., Baroncelli S., Villani P., Cusato M., Cerioli A., De Martino M., Mastroiacovo P., Parazzini F., Vella S. |
| المساهمون: | M. Floridia, E. Tamburrini, G. Masuelli, P. Martinelli, A. Spinillo, G. Liuzzi, A. Vimercati, S. Alberico, A. Maccabruni, C. Pinnetti, V. Frisina, S. Dalzero, M. Ravizza, F. Mori, P. Ortolani, E.R. dalle Nogare, F. Di Lorenzo, G. Sterrantino, M. Meli, S. Polemi, J. Nocentini, M. Baldini, G. Montorzi, M. Mazzetti, P. Rogasi, B. Borchi, F. Vichi, B. Del Pin, E. Pinter, E. Anzalone, R. Marocco, C. Mastroianni, V.S. Mercurio, A. Carocci, E. Grilli, M. Zaramella, B. Mariani, G. Natalini Raponi, G. Guaraldi, G. Nardini, C. Stentarelli, B. Beghetto, A.M. Degli Antoni, A. Molinari, M.P. Crisalli, A. Donisi, M. Piepoli, V. Cerri, G. Zuccotti, V. Giacomet, S. Coletto, F. Di Nello, C. Madia, G. Placido, A. Vivarelli, P. Castelli, F. Savalli, V. Portelli, F. Sabbatini, D. Francisci, L. Bernini, P. Grossi, L. Rizzi, G. Maso, M. Airoud, G. Soppelsa, A. Meloni, M. Dedoni, C. Cuboni, F. Ortu, P. Piano, A. Citernesi, I. Bordoni Vicini, K. Luzi, M. Roccio, A. Miccoli, A. De Gennaro, B. Guerra, F. Cervi, G. Simonazzi, E. Margarito, M.G. Capretti, C. Marsico, G. Faldella, M. Sansone, A. Agangi, A. Capone, M. Maruotti, C. Tibaldi, L. Trentini, T. Todro, I. Cetin, T. Brambilla, V. Savasi, C. Personeni, C. Giaquinto, M. Fiscon, E. Rubino, A. Bucceri, R. Matrone |
| بيانات النشر: | Wiley |
| سنة النشر: | 2016 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | birth weight, HIV, HIV RNA, pregnancy, preterm delivery, health policy, pharmacology (medical), infectious diseases, Settore MED/40 - Ginecologia e Ostetricia |
| الوصف: | Objectives: The aim of the study was to assess the rate, determinants, and outcomes of repeat pregnancies in women with HIV infection. Methods: Data from a national study of pregnant women with HIV infection were used. Main outcomes were preterm delivery, low birth weight, CD4 cell count and HIV plasma viral load. Results: The rate of repeat pregnancy among 3007 women was 16.2%. Women with a repeat pregnancy were on average younger than those with a single pregnancy (median age 30 vs. 33 years, respectively), more recently diagnosed with HIV infection (median time since diagnosis 25 vs. 51 months, respectively), and more frequently of foreign origin [odds ratio (OR) 1.36; 95% confidence interval (CI) 1.10-1.68], diagnosed with HIV infection in the current pregnancy (OR: 1.69; 95% CI: 1.35-2.11), and at their first pregnancy (OR: 1.33; 95% CI: 1.06-1.66). In women with sequential pregnancies, compared with the first pregnancy, several outcomes showed a significant improvement in the second pregnancy, with a higher rate of antiretroviral treatment at conception (39.0 vs. 65.4%, respectively), better median maternal weight at the start of pregnancy (60 vs. 61 kg, respectively), a higher rate of end-of-pregnancy undetectable HIV RNA (60.7 vs. 71.6%, respectively), a higher median birth weight (2815 vs. 2885 g, respectively), lower rates of preterm delivery (23.0 vs. 17.7%, respectively) and of low birth weight (23.4 vs. 15.4%, respectively), and a higher median CD4 cell count (+47 cells/μL), with almost no clinical progression to Centers for Disease Control and Prevention stage C (CDC-C) HIV disease (0.3%). The second pregnancy was significantly more likely to end in voluntary termination than the first pregnancy (11.4 vs. 6.1%, respectively). Conclusions: Younger and foreign women were more likely to have a repeat pregnancy; in women with sequential pregnancies, the second pregnancy was characterized by a significant improvement in several outcomes, suggesting that women with HIV infection who desire multiple ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/28000379; info:eu-repo/semantics/altIdentifier/wos/WOS:000405317000008; journal:HIV MEDICINE; http://hdl.handle.net/2434/484863Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85007326986 |
| DOI: | 10.1111/hiv.12473 |
| الإتاحة: | https://doi.org/10.1111/hiv.12473Test http://hdl.handle.net/2434/484863Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.F0719C78 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/hiv.12473 |
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