دورية أكاديمية

Oral plexiform schwannoma: A case report and relevant immunohistochemical investigation

التفاصيل البيبلوغرافية
العنوان: Oral plexiform schwannoma: A case report and relevant immunohistochemical investigation
المؤلفون: Sergheraert, Johan, Zachar, Dominique, Furon, Vincent, Khonsari, Roman-Hossein, Ortonne, Nicolas, Mauprivez, Cedric
المصدر: SAGE Open Medical Case Reports ; volume 7, page 2050313X1983818 ; ISSN 2050-313X 2050-313X
بيانات النشر: SAGE Publications
سنة النشر: 2019
مصطلحات موضوعية: General Medicine
الوصف: Schwannomas are benign peripheral nerve sheath tumors originating from the Schwann cells. Most schwannomas in the head and neck region are solitary; however, multiple schwannomas affecting one or more nerves suggest a possible association with neurofibromatosis type 2 and schwannomatosis. Plexiform schwannoma is a rare variant of conventional schwannoma that is characterized by intraneural multinodular growth. This grow pattern has also been observed with other neural tumors which may make diagnosis more difficult. Herein, we report the case of a 28-year-old woman who presented a solitary plexiform schwannoma of great palatine nerve. In the present case, we focused on immunohistochemical analysis in daily practice for the differential diagnosis of schwannomas and their mainly morphological mimics, especially with plexiform neurofibroma, granular cell tumor and malignant peripheral nerve sheath tumors. We also discussed on SMARBC1/IN1 marker usefulness in combination with brain magnetic resonance imaging for the distinction of solitary schwannoma from neurofibromatosis type 2 or schwannomatosis.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/2050313x19838184
DOI: 10.1177/2050313X19838184
الإتاحة: https://doi.org/10.1177/2050313x19838184Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.EFD6D49
قاعدة البيانات: BASE