دورية أكاديمية
Refractive Error Change and Overminus Lens Therapy for Childhood Intermittent Exotropia
| العنوان: | Refractive Error Change and Overminus Lens Therapy for Childhood Intermittent Exotropia |
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| المؤلفون: | Alexander, Monsey L, Allen, Megan, Alluri, Sreevardhan, Amster, Deborah M, Anderson, Heather A, Argoubi, Afifa, Astle, William F, Austin, Darrell S, Bailey, Maragaret K, Baker, John D, Beaulieu, Wesley T, Beck, Roy W, Berns, Fabiana, Bhatt, Amit R, Birch, Eileen E, Bitner, Derek P, Bland, Tracy A, Bodack, Marie I, Boente, Charline S, Bohra, Lisa, Bond, Lezlie L, Bothun, Erick D, Boyle, Nicole M, Brafford, Randy C, Castle, Kelly M, Chamberlain, Carolyn, Cheung, Nathan L, Christiansen, Stephen P, Christoff, Alex, Chung, Ida, Cioffi, Katherine R, Clausius, Deborah A, Cobb, Patricia, Collins, Mary Louise Z, Colon, Beth J, Conley, Julie A, Conner, Courtney L, Connolly, Katie S, Cooper, Karen, Crossnoe, Connie J, Crouch, Eric R, Cupit, Shawn L, Curtis, Linda T, Cutrer, Beth M, Davis, Barry, de Alba Campomanes, Alejandra G, De Leon, Erika A, Dean, Trevano W, Diener-West, Marie I, Dillon, Angela C |
| المصدر: | JAMA Ophthalmology ; ISSN 2168-6165 |
| بيانات النشر: | American Medical Association (AMA) |
| سنة النشر: | 2024 |
| الوصف: | Importance Increased myopic shift was found to be associated with 1 year of overminus spectacle treatment for children with intermittent exotropia (IXT). Persistence of myopic shift after discontinuing overminus spectacles is unknown. Objective To compare refractive error change over 3 years in children with IXT originally treated with overminus vs nonoverminus spectacles. Design, Setting, and Participants This study was an 18-month extension of the Trial of Overminus Spectacle Therapy for Intermittent Exotropia cohort, which previously randomized children aged 3 to 10 years with IXT and baseline spherical equivalent refractive error (SER) between −6.00 diopters (D) and 1.00 D to overminus spectacles (−2.50 D for 12 months, −1.25 D for 3 months, and nonoverminus for 3 months) or nonoverminus spectacles. Children were recruited from 56 sites from July 2010 to February 2022. Data were analyzed from February 2022 to January 2024. Interventions After trial completion at 18 months, participants were followed up at 24 and 36 months. Treatment was at investigator discretion from 18 to 36 months. Main Outcomes and Measures Change in SER (cycloplegic retinoscopy) from baseline to 36 months. Results Of 386 children in the Trial of Overminus Spectacle Therapy for Intermittent Exotropia, 223 (57.8%) consented to 18 months of additional follow-up, including 124 of 196 (63.3%) in the overminus treatment group and 99 of 190 (52.1%) in the nonoverminus treatment group. Of 205 children who completed 36-month follow-up, 116 (56.6%) were female, and the mean (SD) age at randomization was 6.2 (2.1) years. Mean (SD) SER change from baseline to 36 months was greater in the overminus group (−0.74 [1.00] D) compared with the nonoverminus group (−0.44 [0.85] D; adjusted difference, −0.36 D; 95% CI, −0.59 to −0.12; P = .003), with 30 of 112 (26.8%) in the overminus group having more than 1 D of myopic shift compared with 14 of 91 (15%) in the nonoverminus group (risk ratio, 1.8; 95% CI, 1.0-3.0). From 12 to 36 months, mean (SD) myopic ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1001/jamaophthalmol.2024.0276 |
| الإتاحة: | https://doi.org/10.1001/jamaophthalmol.2024.0276Test https://jamanetwork.com/journals/jamaophthalmology/articlepdf/2816568/jamaophthalmology_chen_2024_oi_240010_1710346360.55849.pdfTest |
| رقم الانضمام: | edsbas.EE4A154A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1001/jamaophthalmol.2024.0276 |
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