التفاصيل البيبلوغرافية
| العنوان: |
Dietary changes and cognition over 2 years within a multidomain intervention trial-The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) |
| المؤلفون: |
Lehtisalo, Jenni, Levälahti, Esko, Lindström, Jaana, Hänninen, Tuomo, Paajanen, Teemu, Peltonen, Markku, Antikainen, Riitta, Laatikainen, Tiina, Strandberg, Timo, Soininen, Hilkka, Tuomilehto, Jaakko, Kivipelto, Miia, Ngandu, Tiia |
| المساهمون: |
Clinicum, Department of Public Health, University of Helsinki, Timo Strandberg / Principal Investigator, Department of Medicine, HUS Internal Medicine and Rehabilitation |
| بيانات النشر: |
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC |
| سنة النشر: |
2019 |
| المجموعة: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: |
Diet, Cognitive performance, Prevention, Older adults, Growth curve analysis, BASE-LINE CHARACTERISTICS, LIFE-STYLE INTERVENTION, STOP HYPERTENSION DIET, ALZHEIMERS-DISEASE, MEDITERRANEAN DIET, OLDER-ADULTS, DECLINE, DEMENTIA, PATTERNS, RISK, 3112 Neurosciences, 3124 Neurology and psychiatry |
| الوصف: |
Introduction: Association between healthy diet and better cognition is well established, but evidence is limited to evaluate the effect of dietary changes adopted in older age. Methods: We investigated the role of dietary changes in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) with 1260 at-risk participants (60-77 years) who were randomized to intensive multidomain intervention (including dietary counseling) or regular health advice for 2 years. Parallel process latent growth curves of adherence to dietary recommendations and cognitive performance were analyzed. Results: Adherence to healthy diet at baseline predicted improvement in global cognition, regardless of intervention allocation (P = .003). Dietary improvement was associated with beneficial changes in executive function, especially in the intervention group (P = .008; P = .051 for groups combined). Discussion: Dietary changes initiated during the intervention were related to changes in executive function in 2 years. Long-term diet appeared more influential for global cognition. (C) 2018 The Authors. Published by Elsevier Inc. ; Peer reviewed |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
The FINGER trial was supported by the Academy of Finland (Responding to Public Health Challenges Research Programme SALVE; and grant numbers 129395, 129397, 129459, 129421, 129416, 129511, 129401, 259615, 278457); the Finnish Medical Foundation; La Carita Foundation; Alzheimer's Association (HAT-10-173121); Juho Vainio Foundation; Novo Nordisk Foundation; Finnish Social Insurance Foundation; Ministry of Education and Culture Research Grant; EVO/VTR grants of University Hospitals of Kuopio, Oulu and Turku, Seinajoki Central Hospital and Oulu City Hospital for FINGER project; Swedish Research Council; Alzheimer's Research & Prevention Foundation, USA; AXA Research Found; the Sheikha Salama Bint Hamdan Al Nahyan Foundation; Knut and Alice Wallenberg Foundation, Sweden; Center for Innovative Medicine (CIMED) at Karolinska Institutet, Sweden; Stiftelsen Stockholms Sjukhem, Sweden, Konung Gustaf V:s och Drottning Victorias Frimurarstiftelse, Sweden; and Alexander von Humboldt Research award, and a donation from the af Jochnick Foundation. Funders had no role in the design, analysis, or writing of this article.; Lehtisalo , J , Levälahti , E , Lindström , J , Hänninen , T , Paajanen , T , Peltonen , M , Antikainen , R , Laatikainen , T , Strandberg , T , Soininen , H , Tuomilehto , J , Kivipelto , M & Ngandu , T 2019 , ' Dietary changes and cognition over 2 years within a multidomain intervention trial-The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) ' , Alzheimer's & Dementia , vol. 15 , no. 3 , pp. 410-417 . https://doi.org/10.1016/j.jalz.2018.10.001Test; ORCID: /0000-0001-6299-925X/work/55618198; 85062243218; 1d7331b4-f0ae-4688-9e69-297be1922f87; http://hdl.handle.net/10138/300300Test; 000460233800004 |
| الإتاحة: |
http://hdl.handle.net/10138/300300Test |
| حقوق: |
cc_by_nc_nd ; openAccess ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.EE3A615A |
| قاعدة البيانات: |
BASE |
