التفاصيل البيبلوغرافية
| العنوان: |
Ultrashort Peptide Bioinks Support Automated Printing of Large-Scale Constructs Assuring Long-Term Survival of Printed Tissue Constructs |
| المؤلفون: |
Hepi H. Susapto (10032267), Dana Alhattab (10032270), Sherin Abdelrahman (10032273), Zainab Khan (4516978), Salwa Alshehri (10032276), Kowther Kahin (10032279), Rui Ge (1663630), Manola Moretti (2014258), Abdul-Hamid Emwas (1235382), Charlotte A. E. Hauser (10032282) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Space Science, Information Systems not elsewhere classified, tissue fabrication, structure-solidifying process, tissue scaffolds, ultrashort peptide bioinks, deposition process, peptide bioinks, extrusion procedure, encapsulated cells, chondrogenic differentiation, bioprinting procedures, tissue engineering, Large-Scale Constructs Assuring Lon., shape fidelity, cell-embedding printing process, bioink concentrations, structure complexity, cell survival, cell viability, Printed Tissue Constructs, cells point, Ultrashort Peptide Bioinks Support . |
| الوصف: |
We report about rationally designed ultrashort peptide bioinks, overcoming severe limitations in current bioprinting procedures. Bioprinting is increasingly relevant in tissue engineering, regenerative and personalized medicine due to its ability to fabricate complex tissue scaffolds through an automated deposition process. Printing stable large-scale constructs with high shape fidelity and enabling long-term cell survival are major challenges that most existing bioinks are unable to solve. Additionally, they require chemical or UV-cross-linking for the structure-solidifying process which compromises the encapsulated cells, resulting in restricted structure complexity and low cell viability. Using ultrashort peptide bioinks as ideal bodylike but synthetic material, we demonstrate an instant solidifying cell-embedding printing process via a sophisticated extrusion procedure under true physiological conditions and at cost-effective low bioink concentrations. Our printed large-scale cell constructs and the chondrogenic differentiation of printed mesenchymal stem cells point to the strong potential of the peptide bioinks for automated complex tissue fabrication. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/media/Ultrashort_Peptide_Bioinks_Support_Automated_Printing_of_Large-Scale_Constructs_Assuring_Long-Term_Survival_of_Printed_Tissue_Constructs/13640787Test |
| DOI: |
10.1021/acs.nanolett.0c04426.s002 |
| الإتاحة: |
https://doi.org/10.1021/acs.nanolett.0c04426.s002Test |
| حقوق: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.EDD3D428 |
| قاعدة البيانات: |
BASE |
