دورية أكاديمية
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei
| العنوان: | TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei |
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| المؤلفون: | shameer, Sanu, Logan-Klumpler, Flora J., Vinson, Florence, Cottret, Ludovic, Merlet, Benjamin, Achcar, Fiona, Boshart, Michael, Berriman, Matthew, Breitling, Rainer, Bringaud, Frédéric, Bütikofer, Peter, Cattanach, Amy M., Bannerman-Chukualim, Bridget, Creek, Darren J., Crouch, Kathryn, de Koning, Harry P., Denise, Hubert, Ebikeme, Charles, Fairlamb, Alan H., Ferguson, Michael A. J., Ginger, Michael L., Hertz-Fowler, Christiane, Kerkhoven, Eduard J., Maeser, Pascal, Michels, Paul A. M., Nayak, Archana, Nes, David W., Nolan, Derek P., Olsen, Christian, Silva-Franco, Fatima, Smith, Terry K., Taylor, Martin C., Tielens, Aloysius G. M., Urbaniak, Michael D., van Hellemond, Jaap J., Vincent, Isabel M., Wilkinson, Shane R., Wyllie, Susan, Opperdoes, Fred R., Barrett, Michael P., Jourdan, Fabien |
| المساهمون: | ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), The Wellcome Trust Sanger Institute Cambridge, Métabolisme et Xénobiotiques (ToxAlim-MeX), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Laboratoire des interactions plantes micro-organismes (LIPM), Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), University of Glasgow, Ludwig Maximilians University of Munich, University of Manchester Manchester, Centre National de la Recherche Scientifique (CNRS), University of Bern, Monash University, European Molecular Biology Laboratory European Bioinformatics Institute, United Nations Educational, Scientific and Cultural Organization (UNESCO), University of Dundee, Lancaster University, University of Liverpool, Chalmers University of Technology Gothenburg, Sweden, Swiss Tropical and Public Health Institute Basel, University of Edinburgh, TexasTech University, Trinity College Dublin, Biomatters Inc, Partenaires INRAE, University of St Andrews Scotland, London School of Hygiene and Tropical Medicine (LSHTM), Utrecht University Utrecht, Erasmus University Rotterdam, Queen Mary University of London (QMUL), Université Catholique de Louvain = Catholic University of Louvain (UCL), ANR project, European Project: 290080,EC:FP7:PEOPLE,FP7-PEOPLE-2011-ITN,PARAMET(2012) |
| المصدر: | ISSN: 0305-1048. |
| بيانات النشر: | HAL CCSD Oxford University Press |
| سنة النشر: | 2015 |
| المجموعة: | Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
| مصطلحات موضوعية: | [SDV]Life Sciences [q-bio], [SDV.BV]Life Sciences [q-bio]/Vegetal Biology |
| الوصف: | International audience ; The metabolic network of a cell represents the catabolic and anabolic reactions that interconvert small molecules (metabolites) through the activity of enzymes, transporters and non-catalyzed chemical reactions. Our understanding of individual metabolic networks is increasing as we learn more about the enzymes that are active in particular cells under particular conditions and as technologies advance to allow detailed measurements of the cellular metabolome. Metabolic network databases are of increasing importance in allowing us to contextualise data sets emerging from transcriptomic, proteomic and metabolomic experiments. Here we present a dynamic database, TrypanoCyc ( ext-link-type="uri" xlink:href="http://www.metexplore.fr/trypanocycTest/" xlink:type="simple">http://www.metexplore.fr/trypanocycTest/), which describes the generic and condition-specific metabolic network of Trypanosoma brucei, a parasitic protozoan responsible for human and animal African trypanosomiasis. In addition to enabling navigation through the BioCyc-based TrypanoCyc interface, we have also implemented a network-based representation of the information through MetExplore, yielding a novel environment in which to visualise the metabolism of this important parasite. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| ردمك: | 978-0-00-350210-7 0-00-350210-4 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/25300491; info:eu-repo/grantAgreement/EC/FP7/290080/EU/A systematic analysis of parasite metabolism - from metabolism to intervention/PARAMET; hal-02631222; https://hal.inrae.fr/hal-02631222Test; https://hal.inrae.fr/hal-02631222/documentTest; https://hal.inrae.fr/hal-02631222/file/Nucl.%20Acids%20Res.-2015-Shameer-D637-44_1.pdfTest; PRODINRA: 320194; PUBMED: 25300491; WOS: 000350210400095 |
| DOI: | 10.1093/nar/gku944 |
| الإتاحة: | https://doi.org/10.1093/nar/gku944Test https://hal.inrae.fr/hal-02631222Test https://hal.inrae.fr/hal-02631222/documentTest https://hal.inrae.fr/hal-02631222/file/Nucl.%20Acids%20Res.-2015-Shameer-D637-44_1.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.EC4CA46D |
| قاعدة البيانات: | BASE |
| ردمك: | 9780003502107 0003502104 |
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| DOI: | 10.1093/nar/gku944 |