دورية أكاديمية
Optics miniaturization strategy for demanding Raman spectroscopy applications
| العنوان: | Optics miniaturization strategy for demanding Raman spectroscopy applications |
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| المؤلفون: | Ilchenko, Oleksii, Pilhun, Yurii, Kutsyk, Andrii, Slobodianiuk, Denys, Goksel, Yaman, Dumont, Elodie, Vaut, Lukas, Mazzoni, Chiara, Morelli, Lidia, Boisen, Sofus, Stergiou, Konstantinos, Aulin, Yaroslav, Rindzevicius, Tomas, Andersen, Thomas Emil, Lassen, Mikael, Mundhada, Hemanshu, Jendresen, Christian Bille, Philipsen, Peter Alshede, Hædersdal, Merete, Boisen, Anja |
| المصدر: | Ilchenko , O , Pilhun , Y , Kutsyk , A , Slobodianiuk , D , Goksel , Y , Dumont , E , Vaut , L , Mazzoni , C , Morelli , L , Boisen , S , Stergiou , K , Aulin , Y , Rindzevicius , T , Andersen , T E , Lassen , M , Mundhada , H , Jendresen , C B , Philipsen , P A , Hædersdal , M & Boisen , A 2024 , ' Optics miniaturization strategy for demanding Raman spectroscopy applications ' , Nature Communications , vol. .... |
| سنة النشر: | 2024 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| الوصف: | Raman spectroscopy provides non-destructive, label-free quantitative studies of chemical compositions at the microscale as used on NASA's Perseverance rover on Mars. Such capabilities come at the cost of high requirements for instrumentation. Here we present a centimeter-scale miniaturization of a Raman spectrometer using cheap non-stabilized laser diodes, densely packed optics, and non-cooled small sensors. The performance is comparable with expensive bulky research-grade Raman systems. It has excellent sensitivity, low power consumption, perfect wavenumber, intensity calibration, and 7 cm-1 resolution within the 400-4000 cm-1 range using a built-in reference. High performance and versatility are demonstrated in use cases including quantification of methanol in beverages, in-vivo Raman measurements of human skin, fermentation monitoring, chemical Raman mapping at sub-micrometer resolution, quantitative SERS mapping of the anti-cancer drug methotrexate and in-vitro bacteria identification. We foresee that the miniaturization will allow realization of super-compact Raman spectrometers for integration in smartphones and medical devices, democratizing Raman technology. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://portal.findresearcher.sdu.dk/da/publications/cecce2bd-ae18-4954-a0dd-c6bd08848451Test |
| DOI: | 10.1038/s41467-024-47044-7 |
| الإتاحة: | https://doi.org/10.1038/s41467-024-47044-7Test https://portal.findresearcher.sdu.dk/da/publications/cecce2bd-ae18-4954-a0dd-c6bd08848451Test https://findresearcher.sdu.dk/ws/files/259626413/s41467-024-47044-7.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.EB21B8DA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41467-024-47044-7 |
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