دورية أكاديمية
Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain.
| العنوان: | Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain. |
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| المؤلفون: | Leiva-Gea, Isabel, Fernández, Cristina Antúnez, Cardona-Hernandez, Roque, Lozano, Marta Ferrer, Bahíllo-Curieses, Pilar, Arroyo-Díez, Javier, León, María Clemente, Martín-Frías, Maria, Barreiro, Santiago Conde, Delgado, Andrés Mingorance, Sánchez, Jacobo Pérez, Diabetes Group of the Spanish Pediatric Endocrinology Society (SEEP) |
| سنة النشر: | 2022 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | COVID-19, DKA, diabetes onset, type 1 diabetes |
| الوصف: | Objective: To assess the impact of the COVID-19 pandemic and lockdown measures on the presenting characteristics (age at diagnosis, severity, monthly distribution) of newly diagnosed type 1 diabetes in Spanish children. Research DesignandMethods: An ambispective observational multicenter study was conducted in nine Spanish tertiary-level hospitals between January 2015 and March 2021. Inclusion criteria: new cases of type 1 diabetes in children (0-14 years) recording age, sex, date of diagnosis, presence of diabetic ketoacidosis (DKA) at onset, and severity of DKA. Data were compared before and during the pandemic. Results: We registered 1444 new cases of type 1 diabetes in children: 1085 in the pre-pandemic period (2015-2019) and 359 during the pandemic (2020-March 2021). There was a significant increase in the group aged ≤4 years in the pandemic period (chi-squared = 10.986, df 2, p = 0.0041). In 2020-2021, cases of DKA increased significantly by 12% (95% CI: 7.2-20.4%), with a higher percentage of moderate and severe DKA, although this increase was not significant. In 2020, there was a sharp decrease in the number of cases in March, with a progressive increase from May through November, higher than in the same months of the period 2015-2019, highlighting the increase in the number of cases in June, September, and November. The first three months of 2021 showed a different trend to that observed both in the years 2015-2019 and in 2020, with a marked increase in the number of cases. Conclusions: A change in monthly distribution was described, with an increase in DKA at onset of type 1 diabetes. No differences were found in severity, although there were differences in the age distribution, with an increase in the number of cases in children under 4 years of age. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| العلاقة: | http://hdl.handle.net/10668/21326Test; PMC9369057; https://www.mdpi.com/2077-0383/11/15/4338/pdf?version=1659062306Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369057/pdfTest |
| DOI: | 10.3390/jcm11154338 |
| الإتاحة: | https://doi.org/10.3390/jcm11154338Test http://hdl.handle.net/10668/21326Test https://www.mdpi.com/2077-0383/11/15/4338/pdf?version=1659062306Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369057/pdfTest |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; open access |
| رقم الانضمام: | edsbas.EA60BA69 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
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| DOI: | 10.3390/jcm11154338 |