دورية أكاديمية
The role of caspases as executioners of apoptosis
| العنوان: | The role of caspases as executioners of apoptosis |
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| المؤلفون: | Kumar, S., Dorstyn, L., Lim, Y. |
| المصدر: | http://dx.doi.org/10.1042/bst20210751Test. |
| بيانات النشر: | Portland Press |
| سنة النشر: | 2022 |
| المجموعة: | The University of Adelaide: Digital Library |
| مصطلحات موضوعية: | Apoptosome, caspase substrates, caspase-2, death-induced signalling complex, PIDDosome |
| الوصف: | Version of Record published: 23 December 2021 ; Caspases are a family of cysteine aspartyl proteases mostly involved in the execution of apoptotic cell death and in regulating inflammation. This article focuses primarily on the evolutionarily conserved function of caspases in apoptosis. We summarise which caspases are involved in apoptosis, how they are activated and regulated, and what substrates they target for cleavage to orchestrate programmed cell death by apoptosis. ; Sharad Kumar, Loretta Dorstyn and Yoon Lim |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0300-5127 1470-8752 |
| العلاقة: | http://purl.org/au-research/grants/nhmrc/1021456Test; http://purl.org/au-research/grants/nhmrc/1041807Test; http://purl.org/au-research/grants/nhmrc/1043057Test; http://purl.org/au-research/grants/nhmrc/GNT1156601Test; http://purl.org/au-research/grants/nhmrc/1103006Test; http://purl.org/au-research/grants/nhmrc/2007739Test; Biochemical Society Transactions, 2022; 50(1):33-45; https://hdl.handle.net/2440/134297Test; Kumar, S. [0000-0001-7126-9814] |
| DOI: | 10.1042/bst20210751 |
| الإتاحة: | https://doi.org/10.1042/bst20210751Test https://hdl.handle.net/2440/134297Test |
| حقوق: | © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society |
| رقم الانضمام: | edsbas.E9A90163 |
| قاعدة البيانات: | BASE |
| تدمد: | 03005127 14708752 |
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| DOI: | 10.1042/bst20210751 |