التفاصيل البيبلوغرافية
| العنوان: |
The Diagnostic Challenges and Clinical and Serological Outcome in Patients Hospitalized for Suspected Lyme Neuroborreliosis |
| المؤلفون: |
Violeta Briciu, Mirela Flonta, Daniel Leucuța, Mihaela Lupșe |
| المصدر: |
Microorganisms; Volume 10; Issue 7; Pages: 1392 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
antibiotic treatment, B. burgdorferi intrathecal antibody index, Borrelia burgdorferi sensu lato, clinical outcome, Lyme neuroborreliosis, serological profile |
| جغرافية الموضوع: |
agris |
| الوصف: |
The aim of our study was to evaluate the differential diagnosis and clinical/serological outcome to antibiotic treatment in patients hospitalized for suspected Lyme neuroborreliosis (LNB). A prospective study included patients hospitalized in a Romanian hospital between March 2011 and October 2012 with neurological symptoms, positive laboratory tests for Borrelia burgdorferi, cerebrospinal fluid (CSF) analysis, and no previous treatment for LNB. A questionnaire was completed for each patient at admission, at the end of treatment, and 3 months later. Patients were treated with antibiotic therapy (ceftriaxone/cefotaxime), irrespective of CSF analysis results. A symptomatic scoring scale was used for the follow-up. Out of the 42 patients included, no patient fulfilled criteria for definite LNB; 7 patients were classified as possible LNB; and in 33 patients, LNB was excluded. Two patients could not be classified (insufficient amount of CSF). Clinical follow-up suggested a better response to therapy in the group of patients with possible LNB than in the group with LNB excluded. The patients’ differential diagnosis and serological follow-up are presented. Patients investigated for suspected LNB present diverse clinical manifestations and comorbidities that complicate differential diagnosis. LNB may be misdiagnosed if CSF analysis is not performed. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Parasitology; https://dx.doi.org/10.3390/microorganisms10071392Test |
| DOI: |
10.3390/microorganisms10071392 |
| الإتاحة: |
https://doi.org/10.3390/microorganisms10071392Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.E996661E |
| قاعدة البيانات: |
BASE |
