دورية أكاديمية
Solvothermal synthesis and characterization of ytterbium/iron mixed oxide nanoparticles with potential functionalities for applications as multiplatform contrast agent in medical image techniques
| العنوان: | Solvothermal synthesis and characterization of ytterbium/iron mixed oxide nanoparticles with potential functionalities for applications as multiplatform contrast agent in medical image techniques |
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| المؤلفون: | Yeste, M. P., Fernandez-Ponce, C., Felix, E., Tinoco, M., Fernandez-Cisnal, R., Garcia-Villar, C., Pfaff, C., Kriwet, J., Natividad, E., Cauqui, M. A., Garcia-Cozar, F., Litran, R., Bomati-Miguel, O. |
| المساهمون: | Yeste, M. P. Univ Cadiz, Fac Sci, Dept Mat Sci & Met Engn & Inorgan Chem, Cadiz 11510, Spain, Cauqui, M. A. Univ Cadiz, Fac Sci, Dept Mat Sci & Met Engn & Inorgan Chem, Cadiz 11510, Spain, Yeste, M. P. Univ Cadiz, IMEYMAT Inst Res Electron Microscopy & Mat, Cadiz 11510, Spain, Felix, E. Univ Cadiz, IMEYMAT Inst Res Electron Microscopy & Mat, Cadiz 11510, Spain, Cauqui, M. A. Univ Cadiz, IMEYMAT Inst Res Electron Microscopy & Mat, Cadiz 11510, Spain, Litran, R. Univ Cadiz, IMEYMAT Inst Res Electron Microscopy & Mat, Cadiz 11510, Spain, Bomati-Miguel, O. Univ Cadiz, IMEYMAT Inst Res Electron Microscopy & Mat, Cadiz 11510, Spain, Fernandez-Ponce, C. Univ Cadiz, Dept Biomed Biotechnol & Publ Hlth, Cadiz, Spain, Fernandez-Cisnal, R. Univ Cadiz, Dept Biomed Biotechnol & Publ Hlth, Cadiz, Spain, Garcia-Cozar, F. Univ Cadiz, Dept Biomed Biotechnol & Publ Hlth, Cadiz, Spain, Fernandez-Ponce, C. Inst Biomed Res Cadiz INIBICA, Cadiz, Spain, Fernandez-Cisnal, R. Inst Biomed Res Cadiz INIBICA, Cadiz, Spain, Garcia-Villar, C. Inst Biomed Res Cadiz INIBICA, Cadiz, Spain, Garcia-Cozar, F. Inst Biomed Res Cadiz INIBICA, Cadiz, Spain, Tinoco, M. Univ Complutense Madrid, ICTS Ctr Nacl Microscopia Elect, Madrid 28040, Spain, Felix, E. Univ Cadiz, Fac Sci, Dept Condensed Matter Phys, Cadiz 11510, Spain, Litran, R. Univ Cadiz, Fac Sci, Dept Condensed Matter Phys, Cadiz 11510, Spain, Bomati-Miguel, O. Univ Cadiz, Fac Sci, Dept Condensed Matter Phys, Cadiz 11510, Spain, Pfaff, C. Univ Vienna, Fac Earth Sci Geog & Astron, Dept Palaeontol, A-1090 Vienna, Austria, Kriwet, J. Univ Vienna, Fac Earth Sci Geog & Astron, Dept Palaeontol, A-1090 Vienna, Austria, Natividad, E. Univ Zaragoza, Inst Nanociencia & Mat Aragon INMA, CSIC, EINA, Edificio Torres Quevedo,Maria de Luna 3, Zaragoza 50018, Spain, Garcia-Villar, C. Hosp Univ Puerta del Mar, Radiol Dept, Ana Viya Ave 21, Cadiz 11009, Spain, Spanish Ministry of Economy and Competitiveness, Consejeria Salud y Familias. JA Spain, Consejeria Economia, Conocimiento, Empresas y Universidad. JA Spain, MCIN/AEI, MINECO/FEDER |
| بيانات النشر: | Elsevier sci ltd |
| سنة النشر: | 2022 |
| المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
| مصطلحات موضوعية: | Ytterbium -iron nanoparticles, Functionalization, Multiplatform contrast agents, Solvothermal process, CT, MRI, Computed-tomography, Enhancement, Nanoprobe |
| الوصف: | A solvothermal route to prepare Glutathione capped hybrid ytterbium/iron oxide nanoparticles with potential applications as multiplatform contrast agent in medical image techniques has been developed. The influence of ytterbium/iron molar ratio used as precursor, as well as the degree of the autoclave filling on the structural and morphological characteristics of the obtained nanoparticles has been extensively studied. Although all nano -particles present similar composition, with YbFeO3 being the majority phase, size and morphology of the as synthetized nanoparticles are highly influenced by the critical temperature and by the over-saturation reached during the solvothermal process. We have demonstrated that glutathione properly functionalizes the hybrid nanoparticles, increasing their colloidal stability and decreasing their cytotoxicity. Additionally, they show good imaging in magnetic resonance and X-ray computerized tomography, thereby indicating promising potential as a dual contrast agent. This work presents, for the first time, glutathione functionalized ytterbium/iron oxide nanoparticles with potential applications in Biomedicine. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0272-8842 1873-3956 |
| العلاقة: | http://hdl.handle.net/10668/22080Test; https://zaguan.unizar.es/record/118746/files/texto_completo.pdfTest; 863347500002 |
| DOI: | 10.1016/j.ceramint.2022.06.194 |
| الإتاحة: | https://doi.org/10.1016/j.ceramint.2022.06.194Test http://hdl.handle.net/10668/22080Test https://zaguan.unizar.es/record/118746/files/texto_completo.pdfTest |
| حقوق: | Attribution-NonCommercial-NoDerivatives 4.0 International ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; open access |
| رقم الانضمام: | edsbas.E91FE661 |
| قاعدة البيانات: | BASE |
| تدمد: | 02728842 18733956 |
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| DOI: | 10.1016/j.ceramint.2022.06.194 |