دورية أكاديمية
Normal human microbiota and dysbiosis - implications for health and disease ; Normalna ljudska mikrobiota i disbioza - implikacije po zdravlje i bolest
| العنوان: | Normal human microbiota and dysbiosis - implications for health and disease ; Normalna ljudska mikrobiota i disbioza - implikacije po zdravlje i bolest |
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| المؤلفون: | Božić, Dragana, Milenković, Marina, Antić-Stanković, Jelena, Arsenović-Ranin, Nevena, Bufan, Biljana |
| المصدر: | Arhiv za farmaciju |
| بيانات النشر: | Savez farmaceutskih udruženja Srbije Univerzitet u Beogradu - Farmaceutski fakultet |
| سنة النشر: | 2024 |
| المجموعة: | FarFaR - Pharmacy Repository (Univ. of Belgrade, Fac. of Pharmacy) |
| مصطلحات موضوعية: | human microbiota, dysbiosis, commensal bacteria, dysbiosis-associated diseases, humana mikrobiota, disbioza, komensalne bakterije, bolesti povezane sa disbiozom |
| الوصف: | The normal human microbiota, formerly called the "microbial flora," consists of bacteria, fungi, viruses, and parasites that colonise the skin and mucous membranes of the respiratory, gastrointestinal, and genitourinary tracts. The number and diversity of microorganisms varies between different body niches and is greatest in the intestinal tract. The microbiota contributes to the homeostasis of the human organism by preventing colonisation by pathogenic microorganisms, participating in digestive processes and metabolism, and regulating immune functions. Various environmental and genetic factors can lead to an imbalance in the human microbiota, called dysbiosis, which can affect human health. Dysbiosis is usually the result of decreased microbial diversity and a lower number of saprophytic microorganisms, followed by an overgrowth of opportunistic species. The most common diseases directly related to intestinal dysbiosis are antibiotic-associated diarrhoea and pseudomembranous colitis, both of which are associated with the excessive growth of harmful bacteria and Clostridioides difficile following broad-spectrum antibiotic therapy. Dysbiosis is associated with various health conditions or diseases such as acne, psoriasis, eczema, chronic obstructive pulmonary disease, inflammatory bowel disease, obesity, metabolic syndrome, type 2 diabetes, autoimmune diseases and allergies, neurological diseases such as Parkinson's disease, Alzheimer's disease, epilepsy and stroke, depression, anxiety, infertility, preterm birth, and malignancies. ; Normalna ljudska mikrobiota, koja se ranije nazivala „mikroflora“, sastoji se od bakterija, gljivica, virusa i parazita koji kolonizuju kožu i sluzokožu respiratornog, gastrointestinalnog i genitourinarnog trakta. Broj i raznovrsnost mikroorganizama variraju između različitih telesnih niša i najveći su u crevnom traktu. Mikrobiota doprinosi homeostazi ljudskog organizma tako što sprečava kolonizaciju patogenim mikroorganizmima, učestvuje u procesima varenja i metabolizma i reguliše ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0004-1963 |
| العلاقة: | https://farfar.pharmacy.bg.ac.rs/handle/123456789/5582Test; http://farfar.pharmacy.bg.ac.rs/bitstream/id/15752/Normal_human_microbiota_pub_2024.pdfTest |
| DOI: | 10.5937/arhfarm74-46612 |
| الإتاحة: | https://doi.org/10.5937/arhfarm74-46612Test https://farfar.pharmacy.bg.ac.rs/handle/123456789/5582Test http://farfar.pharmacy.bg.ac.rs/bitstream/id/15752/Normal_human_microbiota_pub_2024.pdfTest |
| حقوق: | openAccess ; https://creativecommons.org/licenses/by-sa/4.0Test/ ; BY-SA |
| رقم الانضمام: | edsbas.E8D099A1 |
| قاعدة البيانات: | BASE |
| تدمد: | 00041963 |
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| DOI: | 10.5937/arhfarm74-46612 |