دورية أكاديمية
Thread based microfluidic platform for urinary creatinine analysis
| العنوان: | Thread based microfluidic platform for urinary creatinine analysis |
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| المؤلفون: | Arroyo, Manuel J., Erenas Rodríguez, Miguel María, Orbe Payá, Ignacio De, Dobado Jiménez, José Antonio, Ballester, Pablo, Blondeau, Pascal, Salinas Castillo, Alfonso, Capitán Vallvey, Luis Fermín, Cantrell, Kevin |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2020 |
| المجموعة: | DIGIBUG: Repositorio Institucional de la Universidad de Granada |
| مصطلحات موضوعية: | Optical device, µTAD, Creatinine determination, Density functional theory, Calix[4]pyrrole derivative, Smartphone |
| الوصف: | Creatinine level in urine is a key factor to monitor kidney performance. The use of an alternative microfluidic platform based on cellulose substrates is an interesting option to integrate sample treatment, creatinine re- cognition by ionophore extraction chemistry and quantification by color measurement through consumer electronics imaging devices. The inclusion of ionophore extraction chemistry based on aryl-substituted calix[4] pyrrole synthetic receptor on 8.7 mm long cotton thread permit the sample treatment, optical recognition of creatinine and their quantification by smartphone running app in unfiltered urine samples diluted 1:100 ratio. The device shows a short response time, 30 s, to creatinine over a wide dynamic range (from 1.6× 10 6 to 5 10–2 M) with precision between 2.9–4.3%. The low interference level of representative species in urine is studied and justified by density functional theory (DFT) calculations. ; “Ministerio de Economía y Competitividad” under Project CTQ2016-78754-C2-1-R |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | Sensors & Actuators: B. Chemical 305 (2020) 127407; http://hdl.handle.net/10481/58810Test |
| DOI: | 10.1016/j.snb.2019.127407 |
| الإتاحة: | https://doi.org/10.1016/j.snb.2019.127407Test http://hdl.handle.net/10481/58810Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.E79F0042 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.snb.2019.127407 |
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