التفاصيل البيبلوغرافية
| العنوان: |
Quality of life and depression among HIV‐infected patients receiving efavirenz‐ or protease inhibitor‐based therapy in Senegal |
| المؤلفون: |
Poupard, M, Ngom Gueye, NF, Thiam, D, Ndiaye, B, Girard, PM, Delaporte, E, Sow, PS, Landman, R |
| المصدر: |
HIV Medicine ; volume 8, issue 2, page 92-95 ; ISSN 1464-2662 1468-1293 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2007 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Background Efavirenz has been associated with neuropsychiatric disorders, but little is known about depression and quality of life in sub‐Saharan Africa, where nonnucleoside reverse transcriptase inhibitor (NNRTI)‐based regimens are still the first‐line treatment recommended by the World Heath Organization (WHO) and are widely prescribed. Methods In a cross‐sectional study, we evaluated quality of life and depression among Senegalese patients receiving efavirenz‐ or protease inhibitor (PI)‐based regimens. Two hundred consecutive patients who had been taking highly active antiretroviral therapy (HAART) for more than 6 months were asked to complete a questionnaire. Results According to the Center for Epidemiologic Studies Depression Scale (CES‐D), 18% had depression (19% for patients on a PI‐based regimen and 17% for patients on efavirenz‐based treatment). Fifty‐nine per cent of the patients reported no health problems in the past 4 weeks. A quarter of patients had sleep disorders. Moderate or slight adverse events were reported by 28.5% of patients. Conclusions Quality of life and depression scores remained good in both study groups. However, quality of life and depression should be monitored in follow‐up of HIV‐infected patients in sub‐Saharan Africa. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/j.1468-1293.2007.00435.x |
| الإتاحة: |
https://doi.org/10.1111/j.1468-1293.2007.00435.xTest |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.E6A09F6A |
| قاعدة البيانات: |
BASE |
