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Modeling risk factors for sleep- And adiposity-related cardiometabolic disease: Protocol for the short sleep undermines cardiometabolic health (slumbrx) observational study

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العنوان: Modeling risk factors for sleep- And adiposity-related cardiometabolic disease: Protocol for the short sleep undermines cardiometabolic health (slumbrx) observational study
المؤلفون: Knowlden, A.P., Higginbotham, J.C., Grandner, M.A., Allegrante, J.P.
المساهمون: Department of Psychiatry, College of Medicine, University of Arizona
المصدر: JMIR Research Protocols
بيانات النشر: JMIR Publications Inc.
سنة النشر: 2021
المجموعة: The University of Arizona: UA Campus Repository
مصطلحات موضوعية: Abdominal obesity-metabolic syndrome, Adiposity, Body composition, Body fat distribution, Insufficient sleep syndrome, Observational study, Short sleeper syndrome, Sleep deprivation
الوصف: Background: Obesity and short sleep duration are significant public health issues. Current evidence suggests that these conditions are associated with cardiovascular disease, metabolic syndrome, inflammation, and premature mortality. Increased interest in the potential link between obesity and short sleep duration, and its health consequences, has been driven by the apparent parallel increase in the prevalence of both conditions in recent decades, their overlapping association with cardiometabolic outcomes, and the potential causal connection between the two health issues. The SLUMBRx (Short Sleep Undermines Cardiometabolic Health) study seeks to contribute to the development of a comprehensive adiposity-sleep model while laying the groundwork for a future research program that will be designed to prevent and treat adiposity- and sleep-related cardiometabolic disease risk factors. Objective: This SLUMBRx study aims to address 4 topics pertinent to the adiposity-sleep hypothesis: The relationship between adiposity and sleep duration; sex-based differences in the relationship between adiposity and sleep duration; the influence of adiposity indices and sleep duration on cardiometabolic outcomes; and the role of socioecological factors as effect modifiers in the relationship between adiposity indices, sleep, and cardiometabolic outcomes. Methods: SLUMBRx will employ a large-scale survey (n=1000), recruiting 159 participants (53 normal weight, 53 overweight, and 53 obese) to be assessed in 2 phases. Results: SLUMBRx was funded by the National Institutes of Health, Heart, Lung, and Blood Institute through a K01 grant award mechanism (1K01HL145128-01A1) on July 23, 2019. Institutional Review Board (IRB) approval for the research project was sought and obtained on July 10, 2019. Phase 1 of SLUMBRx, the laboratory-based component of the study, will gather objective adiposity indices (air displacement plethysmography and anthropometrics) and cardiometabolic data (blood pressure, pulse wave velocity and pulse wave ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1929-0748
العلاقة: Knowlden, A. P., Higginbotham, J. C., Grandner, M. A., & Allegrante, J. P. (2021). Modeling Risk Factors for Sleep-and Adiposity-Related Cardiometabolic Disease: Protocol for the Short Sleep Undermines Cardiometabolic Health (SLUMBRx) Observational Study. JMIR research protocols, 10(3), e27139.; http://hdl.handle.net/10150/659917Test; JMIR Research Protocols
DOI: 10.2196/27139
الإتاحة: https://doi.org/10.2196/27139Test
http://hdl.handle.net/10150/659917Test
حقوق: Copyright © Adam P Knowlden, John C Higginbotham, Michael A Grandner, John P Allegrante. Originally published in JMIR Research Protocols (http://www.researchprotocols.orgTest), 09.03.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0Test/). ; https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.E5C5E89
قاعدة البيانات: BASE
الوصف
تدمد:19290748
DOI:10.2196/27139