التفاصيل البيبلوغرافية
| العنوان: |
Immunohistochemical Localization of Ornithine Decarboxylase in Human Skin |
| المؤلفون: |
Verrando, Patrick, Juhlin, Lenhart, Lacour, Jean‐Philippe, Ortonne, Jean‐Paul |
| المصدر: |
The Journal of Dermatology ; volume 14, issue 2, page 112-117 ; ISSN 0385-2407 1346-8138 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
1987 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
The localization of ornithine decarboxylase (ODC) in human skin and cultured keratinocytes was studied with an immuno‐histochemical method. ODC was found in the epidermis, hair follicles, sweat glands and errector muscles. Irritation induced by stripping or UV‐B irradiation did not change the staining pattern in the epidermis. In psoriasis, the staining was most marked at the tip of the epidermal rete ridges. In basal cell carcinoma, there was a homogeneous labelling of the tumor cells and, in squamous cell carcinoma, the labelling was strong but less homogeneous. Melanoma and dermal naevus also positively stained for ODC. Cultured human keratinocytes also showed ODC positive immunofluorescence. This technique detects the ODC antigen present rather than levels of ODC activity. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/j.1346-8138.1987.tb03542.x |
| الإتاحة: |
https://doi.org/10.1111/j.1346-8138.1987.tb03542.xTest |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.E3D584C3 |
| قاعدة البيانات: |
BASE |
