دورية أكاديمية
COMPLEXO:identifying the missing heritability of breast cancer via next generation collaboration
| العنوان: | COMPLEXO:identifying the missing heritability of breast cancer via next generation collaboration |
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| المؤلفون: | Southey, Melissa C, Park, Daniel J, Nguyen-Dumont, Tu, Campbell, Ian, Thompson, Ella, Trainer, Alison H, Chenevix-Trench, Georgia, Simard, Jacques, Dumont, Martine, Soucy, Penny, Thomassen, Mads, Jønson, Lars, Pedersen, Inge S, Hansen, Thomas Vo, Nevanlinna, Heli, Khan, Sofia, Sinilnikova, Olga, Mazoyer, Sylvie, Lesueur, Fabienne, Damiola, Francesca, Schmutzler, Rita, Meindl, Alfons, Hahnen, Eric, Dufault, Michael R, Chris Chan, Tl, Kwong, Ava, Barkardóttir, Rosa, Radice, Paolo, Peterlongo, Paolo, Devilee, Peter, Hilbers, Florentine, Benitez, Javier, Kvist, Anders, Törngren, Therese, Easton, Douglas, Hunter, David, Lindstrom, Sara, Kraft, Peter, Zheng, Wei, Gao, Yu-Tang, Long, Jirong, Ramus, Susan, Feng, Bing-Jian, Weitzel, Jeffrey N, Nathanson, Katherine, Offit, Kenneth, Joseph, Vijai, Robson, Mark, Schrader, Kasmintan, Wang, San Ming |
| المصدر: | Southey , M C , Park , D J , Nguyen-Dumont , T , Campbell , I , Thompson , E , Trainer , A H , Chenevix-Trench , G , Simard , J , Dumont , M , Soucy , P , Thomassen , M , Jønson , L , Pedersen , I S , Hansen , T V , Nevanlinna , H , Khan , S , Sinilnikova , O , Mazoyer , S , Lesueur , F , Damiola , F , Schmutzler , R , Meindl , A , Hahnen , E , Dufault , .... |
| سنة النشر: | 2013 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: | Breast Neoplasms/genetics, Female, Genetic Linkage, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Mutation |
| الوصف: | Linkage analysis, positional cloning, candidate gene mutation scanning and genome-wide association study approaches have all contributed significantly to our understanding of the underlying genetic architecture of breast cancer. Taken together, these approaches have identified genetic variation that explains approximately 30% of the overall familial risk of breast cancer, implying that more, and likely rarer, genetic susceptibility alleles remain to be discovered. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://portal.findresearcher.sdu.dk/da/publications/2d69ea4f-f49c-4f9f-a332-0ce0d8fbeac2Test |
| DOI: | 10.1186/bcr3434 |
| الإتاحة: | https://doi.org/10.1186/bcr3434Test https://portal.findresearcher.sdu.dk/da/publications/2d69ea4f-f49c-4f9f-a332-0ce0d8fbeac2Test http://breast-cancer-research.com/content/pdf/bcr3434.pdfTest |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.E2499A1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/bcr3434 |
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