دورية أكاديمية
Resection rate and operability of elderly patients with non-small cell lung cancer: Nationwide study from 1991 to 2014.
| العنوان: | Resection rate and operability of elderly patients with non-small cell lung cancer: Nationwide study from 1991 to 2014. |
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| المؤلفون: | Baldvinsson, Kristjan, Oskarsdottir, Gudrun Nina, Orrason, Andri Wilberg, Halldorsson, Hannes, Thorsteinsson, Hunbogi, Sigurdsson, Martin Ingi, Jonsson, Steinn, Gudbjartsson, Tomas |
| المساهمون: | 1 Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland Show the Organization-Enhanced name(s) 2 Univ Iceland, Fac Med, Reykjavik, Iceland Show the Organization-Enhanced name(s) 3 Brigham & Womens Hosp, Dept Anesthesiol, 75 Francis St, Boston, MA 02115 USA 4 Landspitali Univ, Dept Pulmonol, Reykjavik, Iceland |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2017 |
| المجموعة: | Hirsla - Landspítali University Hospital research archive |
| مصطلحات موضوعية: | Lungnakrabbamein, Aldraðir, Skurðlækningar, PAD12, TAS12, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung, Female, Follow-Up Studies, Forecasting, Humans, Iceland, Incidence, Lung Neoplasms, Male, Neoplasm Staging, Pneumonectomy, Population Surveillance, Retrospective Studies, Survival Rate, Treatment Outcome |
| الوصف: | To access publisher's full text version of this article click on the hyperlink below ; An increasing number of elderly patients are diagnosed with non-small cell lung cancer (NSCLC). We compared the surgical resection rate, operability and survival in this age group (≥75 years) to younger patients using centralized databases in Iceland. ; The study population comprised all patients diagnosed with NSCLC in Iceland from 1991 to 2014. A total of 140 elderly patients (≥75 years) with NSCLC underwent pulmonary resection and were compared with 550 surgically resected patients less than 75 years, with respect to resection rate, short and long-term survival and complications of surgery. Reasons for exclusion from surgery were registered for elderly surgical candidates (stages IA-IIB). ; Surgical resection rate in the elderly group was 18% compared to 32% in the younger age group ( P < 0.001). The most frequent reasons for not operating on elderly patients in stages IA-IIB were poor pulmonary function (58%), heart disease (17%) or multiple comorbidities (17%). The rate of major complications following surgery was comparable in the elderly versus the younger age group, 13 vs 11%, respectively ( P = 0.578). The same was true for 30 day mortality (2 vs 1%, P = 0.397). Five-year overall survival was 40% vs 44% ( P = 0.019) and cancer-specific survival 51% vs 50% ( P = 0.802). ; Elderly patients with resectable NSCLC according to stage are frequently excluded from surgery due to comorbid conditions. Although the operated patients may represent a selected group, their favourable 30-day and long-term survival indicate that more elderly patients with NSCLC could be operated on. ; Landspitali University Research Fund RANNIS, The Icelandic center for Research |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1569-9285 |
| العلاقة: | https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/icvts/24/5/10.1093_icvts_ivw415/4/ivw415.pdf?Expires=1509558501&Signature=MAuTJh1v4Cd59g3DtQDnclp0uapfvuZ7lEcwFU7q5VsriovLPL7xkX53AXnqls~tSvN0Y9uMuxDDpHN9lMjBP~kICY7Oen6rKdaZgWFhn7OG8PqOBCjb0L9lsE-mSvYxUVjLiaMM2L2wHnqIGo0let2FaItXCEFkbV8ORg1nAZXDtXxoRzqiJVMjr2rwEGJhqGo8BkPaMk7GJloafP9bTx5awfuEsYGJLJWM-hSKJCyBrWBS51FmHWRy1zCGv5WUKlo4Po~b6QjgmTzS4VSukJbph1RhRHuWV4XbOFaT2bkCR1N~kZjTuITWJqQ10spddpZHckJzR8GIOeI2qv78rg__&Key-Pair-Id=APKAIUCZBIA4LVPAVW3QTest; Resection rate and operability of elderly patients with non-small cell lung cancer: Nationwide study from 1991 to 2014. 2017, 24 (5):733-739 Interact Cardiovasc Thorac Surg; http://hdl.handle.net/2336/620336Test; Interactive cardiovascular and thoracic surgery |
| DOI: | 10.1093/icvts/ivw415 |
| الإتاحة: | https://doi.org/10.1093/icvts/ivw415Test http://hdl.handle.net/2336/620336Test |
| حقوق: | Archived with thanks to Interactive cardiovascular and thoracic surgery ; Landspitali Access - LSH-aðgangur |
| رقم الانضمام: | edsbas.E1E7F1F1 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 15699285 |
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| DOI: | 10.1093/icvts/ivw415 |