دورية أكاديمية
Allergic contact dermatitis caused by isobornyl acrylate in the Enlite glucose sensor and the Paradigm MiniMed Quick-set insulin infusion set.
العنوان: | Allergic contact dermatitis caused by isobornyl acrylate in the Enlite glucose sensor and the Paradigm MiniMed Quick-set insulin infusion set. |
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المؤلفون: | Herman, Anne, Baeck, Marie, de Montjoye, Laurence, Bruze, Magnus, Giertz, Emil, Goossens, An, Mowitz, Martin |
المساهمون: | UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service de dermatologie |
المصدر: | Contact dermatitis, Vol. 81, no.6, p. 432-437 (2019) |
بيانات النشر: | Wiley |
سنة النشر: | 2019 |
المجموعة: | DIAL@UCL (Université catholique de Louvain) |
مصطلحات موضوعية: | Acrylates, Allergic contact dermatitis, Delayed hypersensitivity, Glucose sensor, Insulin pump, Isobornyl acrylate, Medical device |
الوصف: | BACKGROUND: The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this sensor has been identified as one of the culprit allergens. OBJECTIVES: To report on the presence of IBOA in devices produced by Medtronic, namely, the Enlite sensor and the insulin infusion set Paradigm MiniMed Quick-set. PATIENTS AND METHODS: Five patients reacting to the glucose sensor Enlite and/or the insulin infusion set Paradigm MiniMed Quick-set observed in three clinics (two Belgian and one Swedish) were patch tested with the baseline and other series, as well as with IBOA; four of them also with pieces of adhesive patches from the devices, and two with a thin layer chromatogram of Enlite glucose sensor extracts. Gas chromatography-mass spectrometry (GC-MS) analyses were performed. RESULTS: Four patients reacted to IBOA and one to colophonium, a known allergen in Enlite, and three to the adhesive part of the sensor or the insulin infusion set. IBOA was identified in the sensor by GC-MS, and its presence was indicated in the infusion set. CONCLUSIONS: IBOA is a contact allergen in Enlite glucose sensor, and likely also in the infusion set. Therefore, these devices are not suitable alternatives for patients sensitized to the FreeStyle Libre sensor. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 0105-1873 1600-0536 |
العلاقة: | boreal:225644; http://hdl.handle.net/2078.1/225644Test; info:pmid/31385313; urn:ISSN: 0105-1873; urn:EISSN:1600-0536 |
DOI: | 10.1111/cod.13374 |
الإتاحة: | https://doi.org/10.1111/cod.13374Test http://hdl.handle.net/2078.1/225644Test |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.E1E23AFE |
قاعدة البيانات: | BASE |
تدمد: | 01051873 16000536 |
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DOI: | 10.1111/cod.13374 |